LZTR1 and AATF

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		LZTR1	AATF
Description		leucine zipper like transcription regulator 1	apoptosis antagonizing transcription factor
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Endomembrane System Cul3-RING Ubiquitin Ligase Complex Recycling Endosome Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Nuclear Transcription Factor Complex
	Molecular Function	DNA-binding Transcription Factor Activity Ras GTPase Binding	RNA Binding Protein Binding Protein Kinase Binding Leucine Zipper Domain Binding Tau Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Anatomical Structure Morphogenesis Protein Ubiquitination Negative Regulation Of Ras Protein Signal Transduction	Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Regulation Of Mitotic Cell Cycle Negative Regulation Of Superoxide Anion Generation Ribosome Biogenesis Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Apoptotic Signaling Pathway
Pathways			NRAGE signals death through JNK
Drugs
Diseases
GWAS			Body mass index ( 26426971) Erectile dysfunction ( 30583798) Obesity-related traits ( 23251661)
Interacting Genes		54 interacting genes: AATF ANKRD53 ASB12 BMPR1B CEBPZ CHAF1A CNOT6L E2F8 EHMT1 FANK1 HCLS1 HDAC4 HRAS IKBKG KDM2B KRAS L3MBTL3 MCM3 MED16 MED7 MRAS MYBL2 NR1H3 NRAS PAPOLG PARP1 POLR1B POLR2B POLR2E RAI1 RERE RUVBL1 SCMH1 SND1 SP100 SREBF2 SSX4 STAT1 SUGP2 TAF11 TBX2 TCF19 TFAP2B TRIM5 TUBGCP4 WWP1 ZBTB1 ZNF137P ZNF175 ZNF451 ZNF490 ZNF584 ZNF714 ZZZ3	33 interacting genes: ATM ATR AURKA CCL5 CCL7 CHEK1 CHEK2 CPD DAPK3 DAZAP2 EFNB3 FBXO7 HIPK2 LDOC1 LZTR1 MAPT MPHOSPH6 MPP6 MYO1D NEDD4L NGDN NOS2 NPTN PAWR PCBD2 POLR2J RB1 RELA SMAD3 SP1 SS18L1 TSG101 ZNF468
Entrez ID		8216	26574
HPRD ID		08992	12236
Ensembl ID		ENSG00000099949	ENSG00000275700
Uniprot IDs		A0A384NL67 Q8N653	Q9NY61
PDB IDs			5W6A
Enriched GO Terms of Interacting Partners?
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