ATRIP and C1orf94

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ATRIP	C1orf94
Description		ATR interacting protein	chromosome 1 open reading frame 94
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm
	Molecular Function	Protein Binding K63-linked Polyubiquitin Modification-dependent Protein Binding	Protein Binding
	Biological Process	DNA Damage Checkpoint DNA Replication DNA Repair Interstrand Cross-link Repair Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Fanconi Anemia Pathway Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)	Generalized epilepsy ( 22949513) Lateral ventricle temporal horn volume ( 31530798) Pediatric nonalcoholic steatohepatitis ( 28918882) Sleep duration (short sleep) ( 30846698)
Interacting Genes		21 interacting genes: BRCA1 C1orf94 CCDC28B CDC23 CDC6 CDK16 CEP164 CINP FAAP100 FAM156A LNX1 METTL21A MID2 MOS MX2 POLR1C PRKDC RPA3 SCG2 SPRY2 TASOR2	66 interacting genes: ACTN3 AKAP9 ATRIP ATXN1 BANP BOLA1 BOLL BYSL C1orf109 CARD9 CCHCR1 CCNJL CDKN2D CFAP206 CLK1 CRK CRYBA4 DAB1 DAZAP2 DGCR6 DMRTB1 DOK6 DTX2 FAM168A GCC1 GORASP2 GRB2 GSE1 HGS HNRNPF IPO11 KLHL32 LMO2 MAGED1 MAPK1IP1L MAPK9 MEIS2 MVP NFKBID NGB NR3C1 OAZ3 OIP5 PITX1 PLEKHB2 PRKAG1 PRR20A R3HDM2 RAD51D RBFOX1 RBFOX2 RBM47 RBPMS RFX2 ROR2 SMAP2 TBX6 TENT5D TLE5 TNPO2 TXNDC9 UBQLN4 USO1 VENTX VPS37C YES1
Entrez ID		84126	84970
HPRD ID			11310
Ensembl ID		ENSG00000164053	ENSG00000142698
Uniprot IDs		A0A024R2U4 A0A024R307 Q8WXE1	Q6P1W5
PDB IDs		4IGK 4NB3 5YZ0
Enriched GO Terms of Interacting Partners?
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