ATRIP and FAAP100

Number of citations of the paper that reports this interaction (PubMedID 23723247)
24

		ATRIP	FAAP100
Description		ATR interacting protein	FA core complex associated protein 100
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Nucleoplasm Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding K63-linked Polyubiquitin Modification-dependent Protein Binding	DNA Binding Protein Binding
	Biological Process	DNA Damage Checkpoint DNA Replication DNA Repair Interstrand Cross-link Repair Regulation Of Signal Transduction By P53 Class Mediator	Interstrand Cross-link Repair
Pathways		Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Fanconi Anemia Pathway Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint	Fanconi Anemia Pathway
Drugs
Diseases
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		21 interacting genes: BRCA1 C1orf94 CCDC28B CDC23 CDC6 CDK16 CEP164 CINP FAAP100 FAM156A LNX1 METTL21A MID2 MOS MX2 POLR1C PRKDC RPA3 SCG2 SPRY2 TASOR2	7 interacting genes: APP ATRIP FANCB FANCF FANCL LINC00839 MDFI
Entrez ID		84126	80233
HPRD ID			07982
Ensembl ID		ENSG00000164053	ENSG00000185504
Uniprot IDs		A0A024R2U4 A0A024R307 Q8WXE1	A4ZI32 Q0VG06
PDB IDs		4IGK 4NB3 5YZ0
Enriched GO Terms of Interacting Partners?
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