ATRIP

Description		ATR interacting protein
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GO Annotations	Cellular Component	Nucleoplasm
	Molecular Function	Protein Binding K63-linked Polyubiquitin Modification-dependent Protein Binding
	Biological Process	DNA Damage Checkpoint DNA Replication DNA Repair Interstrand Cross-link Repair Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Fanconi Anemia Pathway Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		21 interacting genes: BRCA1 C1orf94 CCDC28B CDC23 CDC6 CDK16 CEP164 CINP FAAP100 FAM156A LNX1 METTL21A MID2 MOS MX2 POLR1C PRKDC RPA3 SCG2 SPRY2 TASOR2
Entrez ID		84126
HPRD ID
Ensembl ID		ENSG00000164053
Uniprot IDs		A0A024R2U4 A0A024R307 Q8WXE1
PDB IDs		4IGK 4NB3 5YZ0
Enriched GO Terms of Interacting Partners?
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