ATRIP and TASOR2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		ATRIP	TASOR2
Description		ATR interacting protein	transcription activation suppressor family member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Nucleoplasm Cytosol
	Molecular Function	Protein Binding K63-linked Polyubiquitin Modification-dependent Protein Binding	Protein Binding
	Biological Process	DNA Damage Checkpoint DNA Replication DNA Repair Interstrand Cross-link Repair Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Activation of ATR in response to replication stress HDR through Single Strand Annealing (SSA) Processing of DNA double-strand break ends Presynaptic phase of homologous DNA pairing and strand exchange Fanconi Anemia Pathway Regulation of TP53 Activity through Phosphorylation G2/M DNA damage checkpoint
Drugs
Diseases
GWAS		Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		21 interacting genes: BRCA1 C1orf94 CCDC28B CDC23 CDC6 CDK16 CEP164 CINP FAAP100 FAM156A LNX1 METTL21A MID2 MOS MX2 POLR1C PRKDC RPA3 SCG2 SPRY2 TASOR2	23 interacting genes: ATRIP CARD9 CCDC85B CCNG2 COX5B ERH FBF1 HGS KCTD9 KLHL40 LDOC1 LMO1 MLH1 MORN3 NEK6 POLR1C PPP1R16B PRKAB2 SCAMP1 SMARCB1 STAT3 TRIM23 TRIM42
Entrez ID		84126	54906
HPRD ID			10695
Ensembl ID		ENSG00000164053	ENSG00000108021
Uniprot IDs		A0A024R2U4 A0A024R307 Q8WXE1	Q5VWN6
PDB IDs		4IGK 4NB3 5YZ0
Enriched GO Terms of Interacting Partners?
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