PIAS1 and PRDM1

  • Number of citations of the paper that reports this interaction (PubMedID 22555612)
  • 4
  • Data Source:
  • BioGRID (enzymatic study)

PIAS1

PRDM1

Description protein inhibitor of activated STAT 1 PR/SET domain 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all antimicrotubule drugs) ( 23648065)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065)
  • Carboplatin disposition in epthelial ovarian cancer ( 29367611)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Crohn's disease ( 21102463)
  • Diastolic blood pressure ( 30224653)
  • Monobrow ( 27182965)
  • Multiple myeloma ( 27363682)
  • Response to (pegylated) interferon in HBeAG-positive hepatitis B ( 30715261)
  • Sjögren's syndrome ( 24097067)
  • Systemic lupus erythematosus ( 27399966 23273568 26502338 28714469 19838193 19838195)
  • Systemic sclerosis ( 28314753)
Interacting Genes 107 interacting genes: AKT1 AR ATXN1 AXIN1 BARD1 BRCA1 CASP8 CBS CDK4 CEBPA CEBPE CHUK CNOT7 CREB1 CREBBP CSNK2A1 CSRP2 DCLRE1A DDX21 DDX5 DNM1 DNMT3A ELK3 EP300 ESR1 ESR2 FANCI FHL3 FLI1 GATA4 GLUL GRM8 GSK3B GTF2IRD1 HECTD2 HIC1 HTT IKZF5 JUN KLF3 L3MBTL2 LSM3 MAML1 MBD1 MDC1 MDM2 MITF MSX1 MX1 MYB NCOR1 NFATC1 NIN NR2F2 NR3C2 NR5A1 PAXIP1 PGR PIAS2 PIAS4 PLAG1 PML PPP1CA PPP1CC PRDM1 PRPF40A PSME3 PTK2 PTPN1 QKI RAD54L2 RBBP6 RELA SATB1 SATB2 SERBP1 SGTA SKIL SMAD1 SMAD4 SMAD7 SNAI2 SNIP1 SP3 SPOP SREBF2 STAT1 SUFU SUMO1 SUMO1P1 SUMO2 SUMO3 TBP TERF2 TEX11 TP53 TP73 TRIM27 TRIM5 TRIM55 TRIM63 TSG101 UBE2I UBE2L3 YWHAZ ZNF451 ZNF76 11 interacting genes: ATXN1 EXOSC3 H1-1 H3C15 IKZF3 IRF4 KDM1A PIAS1 TLE1 TLE2 TLE5
Entrez ID 8554 639
HPRD ID 16029 04572
Ensembl ID ENSG00000033800 ENSG00000057657
Uniprot IDs O75925 Q1XBU8 A0A3B3IU23 B4DW27 O75626 Q5T4E8
PDB IDs 1V66 3DAL
Enriched GO Terms of Interacting Partners?
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