ZFY and L3MBTL2

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		ZFY	L3MBTL2
Description		zinc finger protein Y-linked	L3MBTL histone methyl-lysine binding protein 2
Image
GO Annotations	Cellular Component	Nucleoplasm Nucleolus	Nucleus Nucleoplasm
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding	Protein Binding Zinc Ion Binding Methylated Histone Binding Histone Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Chromatin Organization Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition
Pathways			SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6
Drugs		Beta-Cyclohexyl-Alanine PCL-016
Diseases
GWAS			Adventurousness ( 30643258) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 26192919) Depression ( 29700475) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 26192919) Major depressive disorder ( 27479909) Neuroticism ( 29255261 27918536) Schizophrenia ( 25056061 29483656)
Interacting Genes		2 interacting genes: L3MBTL2 ZBTB9	17 interacting genes: BEND7 CYB5R3 H3C1 H4C1 LNX2 MEAF6 MPP3 PAICS PHF10 PIAS1 STAC3 STAM2 TBC1D9B TLE5 TRIM42 ZFP64 ZFY
Entrez ID		7544	83746
HPRD ID		02466	13954
Ensembl ID		ENSG00000067646	ENSG00000100395
Uniprot IDs		P08048	A0A0S2Z5X6 Q969R5
PDB IDs		1KLR 1KLS 1XRZ 5ZNF 7ZNF	2W0T 3CEY 3F70
Enriched GO Terms of Interacting Partners?
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