STAC3 and L3MBTL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		STAC3	L3MBTL2
Description		SH3 and cysteine rich domain 3	L3MBTL histone methyl-lysine binding protein 2
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Voltage-gated Calcium Channel Complex T-tubule Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Synapse	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Identical Protein Binding Metal Ion Binding	Protein Binding Zinc Ion Binding Methylated Histone Binding Histone Binding
	Biological Process	Skeletal Muscle Contraction Neuromuscular Synaptic Transmission Intracellular Signal Transduction Skeletal Muscle Fiber Development Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Localization To Plasma Membrane	Chromatin Organization Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition
Pathways			SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 25056061 29483656)	Adventurousness ( 30643258) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Crohn's disease ( 26192919) Depression ( 29700475) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 26192919) Major depressive disorder ( 27479909) Neuroticism ( 29255261 27918536) Schizophrenia ( 25056061 29483656)
Interacting Genes		19 interacting genes: BAZ2B C1orf35 CSNK2A1 DIP2A EAF1 EAF2 ENKD1 FAM124A FAM133A FAM90A1 JMJD6 L3MBTL2 MAB21L3 NKAPD1 NSD3 PPARA SREK1IP1 ZCCHC10 ZGPAT	17 interacting genes: BEND7 CYB5R3 H3C1 H4C1 LNX2 MEAF6 MPP3 PAICS PHF10 PIAS1 STAC3 STAM2 TBC1D9B TLE5 TRIM42 ZFP64 ZFY
Entrez ID		246329	83746
HPRD ID		11606	13954
Ensembl ID		ENSG00000185482	ENSG00000100395
Uniprot IDs		A0A024RB38 Q96MF2	A0A0S2Z5X6 Q969R5
PDB IDs		2DB6 6B29	2W0T 3CEY 3F70
Enriched GO Terms of Interacting Partners?
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