S100A1 and PLEKHF2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		S100A1	PLEKHF2
Description		S100 calcium binding protein A1	pleckstrin homology and FYVE domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Sarcoplasmic Reticulum Z Disc M Band Protein-containing Complex Neuron Projection	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity S100 Protein Binding Calcium-dependent Protein Binding ATPase Binding	Protein Binding Phosphatidylinositol Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Toll-like Receptor Signaling Pathway Regulation Of Heart Contraction Substantia Nigra Development Intracellular Signal Transduction Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Sprouting Angiogenesis	Protein Transport
Pathways		Regulation of TLR by endogenous ligand
Drugs		Olopatadine
Diseases
GWAS			Radiation response ( 20923822)
Interacting Genes		27 interacting genes: ACTA1 AGER ANXA6 ATP2A2 BIK CACYBP CAPZA1 CEP20 DES FKBP4 GFAP GJA1 MDM2 NIF3L1 PGM1 PLB1 PLEKHF2 PLN PPID PYGM REL RYR1 S100A2 S100A4 S100B S100P SYN1	71 interacting genes: ACY3 AIDA AIMP2 APP APPL1 ARL14EP BEND7 BLOC1S6 BSCL2 CAVIN2 CCDC172 CCDC85B CEP44 CGGBP1 CHIC2 DPPA4 DRAP1 DTX2 DUT ESRP1 FBXO28 FHL3 FOXA1 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HEY1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NKG7 NONO NPM2 PDP1 PEX2 PRDM14 PRKAR1A PRPSAP1 RAB39A RABAC1 RADX RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SEPTIN2 SEPTIN5 SEPTIN6 SETBP1 SFN SPEF1 TBX3 TCN2 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z USF1 ZNF250 ZNF263 ZNF398
Entrez ID		6271	79666
HPRD ID		01489	15147
Ensembl ID		ENSG00000160678	ENSG00000175895
Uniprot IDs		A0A0S2Z4H2 P23297	Q9H8W4
PDB IDs		2L0P 2LHL 2LLS 2LLT 2LLU 2LP2 2LP3 2LUX 2M3W 5K89
Enriched GO Terms of Interacting Partners?
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