DUT and PLEKHF2

Number of citations of the paper that reports this interaction (PubMedID 19060904)
283

Data Source:
BioGRID (two hybrid)

		DUT	PLEKHF2
Description		deoxyuridine triphosphatase	pleckstrin homology and FYVE domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Extracellular Exosome	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane
	Molecular Function	Magnesium Ion Binding RNA Binding DUTP Diphosphatase Activity Protein Binding	Protein Binding Phosphatidylinositol Binding Metal Ion Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process DUMP Biosynthetic Process DNA Replication Nucleobase-containing Small Molecule Interconversion DUTP Catabolic Process	Protein Transport
Pathways
Drugs		Deoxyuridine-5'-Diphosphate 1-{(2S,5S)-4-FLUORO-5-[(TRITYLOXY)METHYL]TETRAHYDROFURAN-2-YL}PYRIMIDINE-2,4(1H,3H)-DIONE
Diseases
GWAS		Blood protein levels ( 30072576) Height ( 31562340) Protein quantitative trait loci ( 18464913) Skin pigmentation ( 28300201)	Radiation response ( 20923822)
Interacting Genes		9 interacting genes: CDK1 ESR1 ESRRA ESRRG NUDT18 PLEKHF2 PPARA PPARD SPATA2	71 interacting genes: ACY3 AIDA AIMP2 APP APPL1 ARL14EP BEND7 BLOC1S6 BSCL2 CAVIN2 CCDC172 CCDC85B CEP44 CGGBP1 CHIC2 DPPA4 DRAP1 DTX2 DUT ESRP1 FBXO28 FHL3 FOXA1 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HEY1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NKG7 NONO NPM2 PDP1 PEX2 PRDM14 PRKAR1A PRPSAP1 RAB39A RABAC1 RADX RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SEPTIN2 SEPTIN5 SEPTIN6 SETBP1 SFN SPEF1 TBX3 TCN2 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z USF1 ZNF250 ZNF263 ZNF398
Entrez ID		1854	79666
HPRD ID		03165	15147
Ensembl ID		ENSG00000128951	ENSG00000175895
Uniprot IDs		A0A0C4DGL3 H0YNW5 P33316	Q9H8W4
PDB IDs		1Q5H 1Q5U 2HQU 3ARA 3ARN 3EHW 4MZ5 4MZ6 5H4J
Enriched GO Terms of Interacting Partners?
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