ZMAT2 and TRIM37

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZMAT2	TRIM37
Description		zinc finger matrin-type 2	tripartite motif containing 37
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GO Annotations	Cellular Component	Nucleus U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome	Cytoplasm Peroxisome Cytosol Aggresome ESC/E(Z) Complex Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	Chromatin Binding Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process	MRNA Splicing, Via Spliceosome	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of NF-kappaB Transcription Factor Activity Histone H2A Monoubiquitination Histone H2A-K119 Monoubiquitination Negative Regulation Of Centriole Replication Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Autoubiquitination Aggresome Assembly
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Major depressive disorder ( 27479909) Schizophrenia ( 28991256 29483656) Systolic blood pressure ( 30224653)	Cognitive function ( 25644384) General cognitive ability ( 29844566) Testicular germ cell tumor ( 23666239)
Interacting Genes		25 interacting genes: AK8 AMH CBY2 CCDC57 CEP76 FSD2 FXR2 GOLGA2 HMBOX1 IKZF1 KRT40 LZTS2 MEOX2 MTUS2 PHC2 SPAG5 SSX2IP TFEC TFIP11 TRAF2 TRIM36 TRIM37 VPS52 ZBTB14 ZBTB8A	63 interacting genes: ANKRD11 APEX2 APTX ARNT2 AXIN1 BYSL CCDC33 CDC20B CDK5RAP2 COPB1 CWF19L2 DDX6 DLGAP5 ELOA2 EWSR1 FAM107A FAM124B FAM161A FAM50B FXR2 H2AC20 H2AC4 IKBKG KAT5 KIAA0408 KIF9 LTBR MAGEB18 MCM10 MCRS1 NGFR NUDT18 PBK PNKP PRC1 RASD1 RHPN1 RIBC2 RNF6 RPL9 RXRB SCNM1 TNFRSF1B TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 UBASH3A UBB UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2U ZMAT2 ZNF329 ZNF417 ZNF655
Entrez ID		153527	4591
HPRD ID		08094	05463
Ensembl ID		ENSG00000146007	ENSG00000108395
Uniprot IDs		Q96NC0	O94972
PDB IDs		5O9Z 6AHD	3LRQ
Enriched GO Terms of Interacting Partners?
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