HDDC3 and TPM3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		HDDC3	TPM3
Description		HD domain containing 3	tropomyosin 3
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GO Annotations	Cellular Component		Stress Fiber Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Actin Filament Actin Cytoskeleton Extracellular Exosome
	Molecular Function	Protein Binding Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase Activity Metal Ion Binding	Molecular_function Protein Binding Actin Filament Binding
	Biological Process		Muscle Contraction Actin Filament Organization Muscle Filament Sliding
Pathways			Striated Muscle Contraction Smooth Muscle Contraction
Drugs			Phenethyl Isothiocyanate
Diseases			Congenital fiber type disproportion (CFTD) Cap myopathy Thyroid cancer Nemaline myopathy
GWAS			Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Platelet count ( 27863252) Smoking initiation (ever regular vs never regular) ( 30679032)
Interacting Genes		10 interacting genes: APP CCDC172 CEP57L1 EXOC5 GKAP1 GOLGA8EP GOLGA8F NMI TNIP1 TPM3	44 interacting genes: ACTA1 ACTB BLOC1S6 C1orf216 CCDC102B CCDC114 CCDC146 CCHCR1 CNN1 DVL2 FAM9C FBXO5 HDDC3 HOOK2 HSF2 IFIT3 IKBIP KCNE1 KIFC3 KXD1 LCA5L LURAP1 MAD1L1 MAGEA11 NEK2 NOD2 OIP5 PBX3 S100A2 S100A4 SMAD3 SUMO4 SYCE1 TFPT THAP1 TLK1 TMOD1 TMOD2 TNNT1 TRAP1 TRIM27 TRIP6 VPS52 WASH3P
Entrez ID		374659	7170
HPRD ID		14635	01840
Ensembl ID		ENSG00000184508	ENSG00000143549
Uniprot IDs		Q8N4P3	A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4I4 B4DQ80 P06753
PDB IDs		3NR1 5VXA	6OTN
Enriched GO Terms of Interacting Partners?
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