VPS72 and HMBOX1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		VPS72	HMBOX1
Description		vacuolar protein sorting 72 homolog	homeobox containing 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck Protein-containing Complex	Nuclear Chromosome, Telomeric Region Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cajal Body Nuclear Body PML Body
	Molecular Function	DNA Binding Protein Binding Histone Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded Telomeric DNA Binding Protein Binding Telomeric DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Somatic Stem Cell Population Maintenance Histone Exchange	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Telomerase Activity Positive Regulation Of Telomerase Activity
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Interacting Genes		7 interacting genes: CALCOCO2 CCDC85B EWSR1 HMBOX1 MDFI PRMT1 STK11	49 interacting genes: ABITRAM AEBP2 APP ATP5PO BYSL C8orf33 CARD9 CBX8 CCNG1 DAB1 DYNLL2 ENTPD2 FAM13C FAM161A FAM74A4 FARS2 FNDC11 FRMD6 FXR2 KAT5 LNX1 MAGEH1 MFAP1 MORF4L1 MRPL11 MRPL28 PIP4K2B PKD1P1 PRKAA1 PRKAA2 RBMY2FP REEP6 RPL9 SAP30L SFR1 SH2D4A SNRPB2 TCEANC UBA6 UBE2Z VPS72 WT1 ZBTB24 ZMAT2 ZNF337 ZNF417 ZNF581 ZNF587 ZNF688
Entrez ID		6944	79618
HPRD ID		02791	07964
Ensembl ID		ENSG00000163159	ENSG00000147421
Uniprot IDs		Q15906	D3DSU2 Q6NT76
PDB IDs		5FUG	2CUF 4J19
Enriched GO Terms of Interacting Partners?
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