SMARCE1 and RALBP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SMARCE1	RALBP1
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	ralA binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Nuclear Chromatin Nucleus Nucleoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex	Cytosol Membrane
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Chromatin Binding Transcription Coactivator Activity RNA Binding Protein Binding N-acetyltransferase Activity Nuclear Receptor Binding Nucleosomal DNA Binding Protein N-terminus Binding	GTPase Activator Activity Protein Binding Ral GTPase Binding Transmembrane Transporter Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances Xenobiotic Transmembrane Transporter Activity Rac GTPase Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Neurogenesis ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Nucleic Acid-templated Transcription	Endocytosis Chemotaxis Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Doxorubicin Transport Drug Transmembrane Export
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	Rho GTPase cycle
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic rhinitis ( 31361310) Asthma ( 30929738 31619474) Asthma (childhood onset) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Eczema ( 31361310)	LDL cholesterol ( 30275531)
Interacting Genes		64 interacting genes: AMOTL2 AR ARID2 BAZ1B BRAP BRMS1 CCDC136 CCDC172 CDR2 CEP170P1 CEP63 CEP70 DISC1 EPS8 ESR1 ESR2 EXOC7 GATA1 GOLGA2 ING5 ITCH JAKMIP2 KIFC3 KLF1 KRT15 KRT31 KRT40 KRTAP10-9 MDM2 MED4 MEOX2 MIPOL1 MRFAP1L1 MTUS2 NBPF22P NCOA1 NCOA2 NCOA3 NOTCH2NLA NR0B2 NR3C1 NUP62 PGR PRMT5 RALBP1 RARB RCOR1 RELB RINT1 SIN3A SIN3B SMAD1 SMARCA4 SPAG5 SRC STX11 SYCE1 TFE3 TFIP11 TNIK TRIM54 TRIP10 TXLNA USHBP1	30 interacting genes: AMOTL2 AP2M1 C1orf216 CASP8 CCNB1 CEP57 FADD GSE1 HOOK2 HSF1 IKBKG PLCG2 PPL PRKACA PRKCA RAC1 RALA RALB REPS1 REPS2 RHOU SMARCE1 SYNJ2BP TBRG1 TFPT TNIP1 TRAF2 TSFM ZBTB38 ZNF707
Entrez ID		6605	10928
HPRD ID		04382	09013
Ensembl ID		ENSG00000073584	ENSG00000017797
Uniprot IDs		A0A024R1S7 Q969G3	Q15311
PDB IDs			2KWH 2KWI 2MBG
Enriched GO Terms of Interacting Partners?
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