SMARCE1 and CDR2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SMARCE1	CDR2
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	cerebellar degeneration related protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Nuclear Chromatin Nucleus Nucleoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex	Cytoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Chromatin Binding Transcription Coactivator Activity RNA Binding Protein Binding N-acetyltransferase Activity Nuclear Receptor Binding Nucleosomal DNA Binding Protein N-terminus Binding	Molecular_function Protein Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Neurogenesis ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic rhinitis ( 31361310) Asthma ( 30929738 31619474) Asthma (childhood onset) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Eczema ( 31361310)
Interacting Genes		64 interacting genes: AMOTL2 AR ARID2 BAZ1B BRAP BRMS1 CCDC136 CCDC172 CDR2 CEP170P1 CEP63 CEP70 DISC1 EPS8 ESR1 ESR2 EXOC7 GATA1 GOLGA2 ING5 ITCH JAKMIP2 KIFC3 KLF1 KRT15 KRT31 KRT40 KRTAP10-9 MDM2 MED4 MEOX2 MIPOL1 MRFAP1L1 MTUS2 NBPF22P NCOA1 NCOA2 NCOA3 NOTCH2NLA NR0B2 NR3C1 NUP62 PGR PRMT5 RALBP1 RARB RCOR1 RELB RINT1 SIN3A SIN3B SMAD1 SMARCA4 SPAG5 SRC STX11 SYCE1 TFE3 TFIP11 TNIK TRIM54 TRIP10 TXLNA USHBP1	43 interacting genes: AMOTL2 ANKRD36BP1 ARNT2 C1orf216 C2CD6 C4orf46 CCDC153 CCHCR1 CDC20 CEP57L1 CHIC2 COX5B EIF4E2 ELOB ENKD1 FAM110A FAM161A FZR1 GMPPA HAUS1 HDAC4 HGS KANSL1 KIFC3 LENG1 LIN37 MORF4L2 MRPL28 NDN NTAQ1 PKN1 RCOR3 RSPH14 SCNM1 SH2D4A SMARCE1 TBC1D22B TCHP TMCC2 TRIM23 TTR TXLNA ZGPAT
Entrez ID		6605	1039
HPRD ID		04382	06681
Ensembl ID		ENSG00000073584	ENSG00000140743
Uniprot IDs		A0A024R1S7 Q969G3	Q01850
PDB IDs
Enriched GO Terms of Interacting Partners?
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