SMARCE1 and KIFC3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		SMARCE1	KIFC3
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	kinesin family member C3
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Nuclear Chromatin Nucleus Nucleoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex	Golgi Apparatus Centrosome Kinesin Complex Microtubule Zonula Adherens Cytoplasmic Vesicle Membrane Extracellular Exosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Chromatin Binding Transcription Coactivator Activity RNA Binding Protein Binding N-acetyltransferase Activity Nuclear Receptor Binding Nucleosomal DNA Binding Protein N-terminus Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Minus-end-directed ATPase Activity
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Neurogenesis ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Nucleic Acid-templated Transcription	Microtubule-based Movement Golgi Organization Visual Perception Zonula Adherens Maintenance Epithelial Cell-cell Adhesion
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic rhinitis ( 31361310) Asthma ( 30929738 31619474) Asthma (childhood onset) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Eczema ( 31361310)
Interacting Genes		64 interacting genes: AMOTL2 AR ARID2 BAZ1B BRAP BRMS1 CCDC136 CCDC172 CDR2 CEP170P1 CEP63 CEP70 DISC1 EPS8 ESR1 ESR2 EXOC7 GATA1 GOLGA2 ING5 ITCH JAKMIP2 KIFC3 KLF1 KRT15 KRT31 KRT40 KRTAP10-9 MDM2 MED4 MEOX2 MIPOL1 MRFAP1L1 MTUS2 NBPF22P NCOA1 NCOA2 NCOA3 NOTCH2NLA NR0B2 NR3C1 NUP62 PGR PRMT5 RALBP1 RARB RCOR1 RELB RINT1 SIN3A SIN3B SMAD1 SMARCA4 SPAG5 SRC STX11 SYCE1 TFE3 TFIP11 TNIK TRIM54 TRIP10 TXLNA USHBP1	93 interacting genes: ABI2 ANXA13 APP ARNT2 ATF2 BCL6 C1orf109 CBX8 CBY2 CCDC102B CCDC136 CCDC28A CCDC33 CDK18 CDR2 CEP55 CEP57L1 CLIP4 COG7 CREB5 CYTH4 DCTN2 DCX DEUP1 DTNBP1 ESRRG FAM124A FANCL FBXO7 FCHSD2 GMCL1 GOLGA2 GORASP2 HAUS1 HSBP1 ICA1L ITGB3BP KANSL1 KDM1A KRT15 KRT19 KRT31 KRT40 KRT5 KRT6A KRT6B KRT6C LENG1 LIN37 LZTS2 MCM7 MED4 MFAP1 MID2 MOS NDEL1 NECAB2 NEDD4 NEDD4L NEFL NUP62 PHC2 PRKAA2 PSMB1 RAD51D RSPH14 SCEL SIAH1 SMARCE1 SNAP29 SOX30 SOX5 SVIL SYCE1 TCEANC TLE5 TNIP1 TPM3 TRAF2 TRIM23 TRIM27 TRIM41 TRIM54 TSG101 TSR2 USP2 ZBTB8A ZGPAT ZNF180 ZNF20 ZNF572 ZNF655 ZNF688
Entrez ID		6605	3801
HPRD ID		04382	05171
Ensembl ID		ENSG00000073584	ENSG00000140859
Uniprot IDs		A0A024R1S7 Q969G3	B7Z5U4 B7Z808 B7Z896 F5H3M2 Q9BVG8
PDB IDs			5WDE
Enriched GO Terms of Interacting Partners?
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