SMARCE1 and EXOC7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SMARCE1	EXOC7
Description		SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	exocyst complex component 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Nuclear Chromatin Nucleus Nucleoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex	Exocyst Microtubule Organizing Center Cytosol Plasma Membrane Membrane Growth Cone Membrane Centriolar Satellite Flemming Body
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Chromatin Binding Transcription Coactivator Activity RNA Binding Protein Binding N-acetyltransferase Activity Nuclear Receptor Binding Nucleosomal DNA Binding Protein N-terminus Binding	Protein Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Neurogenesis ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Nucleic Acid-templated Transcription	Exocytosis Protein Transport Regulation Of Macroautophagy Regulation Of Entry Of Bacterium Into Host Cell
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic rhinitis ( 31361310) Asthma ( 30929738 31619474) Asthma (childhood onset) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Eczema ( 31361310)
Interacting Genes		64 interacting genes: AMOTL2 AR ARID2 BAZ1B BRAP BRMS1 CCDC136 CCDC172 CDR2 CEP170P1 CEP63 CEP70 DISC1 EPS8 ESR1 ESR2 EXOC7 GATA1 GOLGA2 ING5 ITCH JAKMIP2 KIFC3 KLF1 KRT15 KRT31 KRT40 KRTAP10-9 MDM2 MED4 MEOX2 MIPOL1 MRFAP1L1 MTUS2 NBPF22P NCOA1 NCOA2 NCOA3 NOTCH2NLA NR0B2 NR3C1 NUP62 PGR PRMT5 RALBP1 RARB RCOR1 RELB RINT1 SIN3A SIN3B SMAD1 SMARCA4 SPAG5 SRC STX11 SYCE1 TFE3 TFIP11 TNIK TRIM54 TRIP10 TXLNA USHBP1	25 interacting genes: AKTIP ARFGEF2 ARPC1A BBS1 BBS2 BBS4 CCDC85B CDC5L DISC1 DLG3 EXOC2 EXOC4 GRIN2B HGS IFT20 KXD1 PRPF19 RALA RHOQ RTN4IP1 SMARCE1 SSC5D TRAF4 USHBP1 ZC3H14
Entrez ID		6605	23265
HPRD ID		04382	16292
Ensembl ID		ENSG00000073584	ENSG00000182473
Uniprot IDs		A0A024R1S7 Q969G3	B4DJ07 B5MCY9 Q63HP7 Q9UPT5
PDB IDs
Enriched GO Terms of Interacting Partners?
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