RALBP1 and REPS1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (biochemical, affinity chromatography technology, pull down)
HPRD (two hybrid, in vivo, in vitro)

		RALBP1	REPS1
Description		ralA binding protein 1	RALBP1 associated Eps domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane	Cytosol Plasma Membrane Clathrin-coated Pit
	Molecular Function	GTPase Activator Activity Protein Binding Ral GTPase Binding Transmembrane Transporter Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances Xenobiotic Transmembrane Transporter Activity Rac GTPase Binding	Calcium Ion Binding Protein Binding SH3 Domain Binding
	Biological Process	Endocytosis Chemotaxis Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Doxorubicin Transport Drug Transmembrane Export	Receptor-mediated Endocytosis Membrane Organization
Pathways		Rho GTPase cycle	Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		LDL cholesterol ( 30275531)	Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834)
Interacting Genes		30 interacting genes: AMOTL2 AP2M1 C1orf216 CASP8 CCNB1 CEP57 FADD GSE1 HOOK2 HSF1 IKBKG PLCG2 PPL PRKACA PRKCA RAC1 RALA RALB REPS1 REPS2 RHOU SMARCE1 SYNJ2BP TBRG1 TFPT TNIP1 TRAF2 TSFM ZBTB38 ZNF707	13 interacting genes: ATF4 CRK GRB2 HSF1 ITSN2 PIN1 RAB11FIP2 RALA RALB RALBP1 REPS2 TRAPPC2L WWC2
Entrez ID		10928	85021
HPRD ID		09013	09687
Ensembl ID		ENSG00000017797	ENSG00000135597
Uniprot IDs		Q15311	B2R7D3 Q96D71
PDB IDs		2KWH 2KWI 2MBG
Enriched GO Terms of Interacting Partners?
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