CHN2 and RANBP3

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

Data Source:
BioGRID (two hybrid)

		CHN2	RANBP3
Description		chimerin 2	RAN binding protein 3
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GO Annotations	Cellular Component	Cytosol Membrane Synapse	Nucleus Nuclear Pore Nucleoplasm Cytoplasm
	Molecular Function	SH3/SH2 Adaptor Activity GTPase Activator Activity Protein Binding Metal Ion Binding	GTPase Activator Activity Protein Binding Ran GTPase Binding R-SMAD Binding
	Biological Process	Positive Regulation Of Signal Transduction Intracellular Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Protein Export From Nucleus Positive Regulation Of GTPase Activity
Pathways		Rho GTPase cycle
Drugs
Diseases
GWAS		Circulating leptin levels in high cardiovascular risk ( 31766143) CSF tryptophan concentration in tuberculous meningitis ( 29395996) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Facial emotion recognition ( 28608620) Facial emotion recognition (angry faces) ( 28608620) Facial emotion recognition (sad faces) ( 28608620) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Loneliness (linear analysis) ( 27629369) Methadone dose in opioid dependence ( 28115739) Obesity-related traits ( 23251661) Psychosis (atypical) ( 24132900) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		9 interacting genes: BAG6 ERBB3 RAC1 RACGAP1 RANBP3 RB1 SMARCD1 TGFBR1 TP53RK	10 interacting genes: ANKS1A BLZF1 CHN2 KRTAP10-8 MEOX1 MORN4 RAN RCC1 XPO1 ZMIZ2
Entrez ID		1124	8498
HPRD ID		04173	04508
Ensembl ID		ENSG00000106069	ENSG00000031823
Uniprot IDs		A0A2X0TVW3 B3VCF4 B3VCF5 B3VCF6 B3VCF9 B7Z1V0 B7Z1W9 B7Z215 B7Z232 P52757	B7Z7F3 Q53GE1 Q9H6Z4
PDB IDs		1XA6	2CRF 2Y8F 2Y8G 5XZX
Enriched GO Terms of Interacting Partners?
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