KLF1 and SMARCC2

Number of citations of the paper that reports this interaction (PubMedID 11018012)
80

Data Source:
BioGRID (pull down)

		KLF1	SMARCC2
Description		Kruppel like factor 1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm	Nuclear Chromatin Nucleoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding Metal Ion Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Erythrocyte Differentiation Positive Regulation Of Transcription, DNA-templated Maternal Process Involved In Female Pregnancy Cellular Response To Peptide	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways			RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases		Congenital dyserythropoietic anemias (CDAs)
GWAS		Clozapine-induced agranulocytosis ( 25187353) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular hemoglobin concentration ( 27863252) Mean corpuscular volume ( 29403010 27863252) Red blood cell count ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)	Asthma ( 31619474)
Interacting Genes		14 interacting genes: ARID1A CREBBP CSNK2A1 CSNK2A2 EP300 FLI1 HDAC1 PRKACA SMARCA4 SMARCB1 SMARCC1 SMARCC2 SMARCD1 SMARCE1	25 interacting genes: ARF6 ARRB2 ATXN1 ATXN1L BAZ1B CSNK2A1 EWSR1 FUS GATA1 IFTAP ITCH ITSN1 KLF1 MCPH1 NOVA1 PEX14 PHYHIP POLR2C RAB1B RELB SP1 SRGAP3 TAF15 TERF1 TERF2IP
Entrez ID		10661	6601
HPRD ID		07197	03437
Ensembl ID		ENSG00000105610	ENSG00000139613
Uniprot IDs		Q13351	A0A024RB22 F8VXC8 Q8TAQ2
PDB IDs		2L2I 2MBH 2N23
Enriched GO Terms of Interacting Partners?
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