PAPOLG and LZTR1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		PAPOLG	LZTR1
Description		poly(A) polymerase gamma	leucine zipper like transcription regulator 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Membrane Nuclear Body	Golgi Apparatus Endomembrane System Cul3-RING Ubiquitin Ligase Complex Recycling Endosome Membrane
	Molecular Function	RNA Binding Polynucleotide Adenylyltransferase Activity ATP Binding Metal Ion Binding	DNA-binding Transcription Factor Activity Ras GTPase Binding
	Biological Process	MRNA Polyadenylation RNA Polyadenylation	Regulation Of Transcription, DNA-templated Anatomical Structure Morphogenesis Protein Ubiquitination Negative Regulation Of Ras Protein Signal Transduction
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Composite immunoglobulin trait (IgA/IgM) ( 28628107) Crohn's disease ( 22412388) Erectile dysfunction ( 30583798) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Systemic lupus erythematosus ( 28714469)
Interacting Genes		3 interacting genes: LZTR1 NFYA PCBD1	54 interacting genes: AATF ANKRD53 ASB12 BMPR1B CEBPZ CHAF1A CNOT6L E2F8 EHMT1 FANK1 HCLS1 HDAC4 HRAS IKBKG KDM2B KRAS L3MBTL3 MCM3 MED16 MED7 MRAS MYBL2 NR1H3 NRAS PAPOLG PARP1 POLR1B POLR2B POLR2E RAI1 RERE RUVBL1 SCMH1 SND1 SP100 SREBF2 SSX4 STAT1 SUGP2 TAF11 TBX2 TCF19 TFAP2B TRIM5 TUBGCP4 WWP1 ZBTB1 ZNF137P ZNF175 ZNF451 ZNF490 ZNF584 ZNF714 ZZZ3
Entrez ID		64895	8216
HPRD ID		11420	08992
Ensembl ID		ENSG00000115421	ENSG00000099949
Uniprot IDs		Q9BWT3	A0A384NL67 Q8N653
PDB IDs		4LT6
Enriched GO Terms of Interacting Partners?
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