PAPOLG and PCBD1

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		PAPOLG	PCBD1
Description		poly(A) polymerase gamma	pterin-4 alpha-carbinolamine dehydratase 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Membrane Nuclear Body	Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	RNA Binding Polynucleotide Adenylyltransferase Activity ATP Binding Metal Ion Binding	Transcription Coactivator Activity Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding
	Biological Process	MRNA Polyadenylation RNA Polyadenylation	L-phenylalanine Catabolic Process Tetrahydrobiopterin Biosynthetic Process Regulation Of Protein Binding Positive Regulation Of Transcription, DNA-templated Oxidation-reduction Process
Pathways			Phenylalanine metabolism
Drugs			L-erythro-7,8-dihydrobiopterin
Diseases			Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
GWAS		Acne (severe) ( 24927181) Composite immunoglobulin trait (IgA/IgM) ( 28628107) Crohn's disease ( 22412388) Erectile dysfunction ( 30583798) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Systemic lupus erythematosus ( 28714469)	Blood protein levels ( 30072576) Chronotype ( 30696823) Immature fraction of reticulocytes ( 27863252) Microalbuminuria ( 26631737) Obesity-related traits ( 23251661)
Interacting Genes		3 interacting genes: LZTR1 NFYA PCBD1	49 interacting genes: ACIN1 APP BRD7 CACNA1C CALCOCO1 CDK5RAP2 CEBPZ DENND4A DIP2C DVL2 DYRK1B EHMT1 FXR2 GORASP2 GTF3C3 HES4 HNF1A HNF4A KLF13 LNX1 MIS18BP1 NFKB1 NIF3L1 NTAQ1 NUDT18 PAH PAPOLG PCBD2 POLR3A RBL2 RPS24 SAP30 SCMH1 SMARCD1 SOWAHC SUPT5H TFF3 TIMELESS TRIM5 WWP1 ZBTB25 ZNF195 ZNF202 ZNF23 ZNF263 ZNF451 ZNF567 ZNF688 ZNF714
Entrez ID		64895	5092
HPRD ID		11420	00523
Ensembl ID		ENSG00000115421	ENSG00000166228
Uniprot IDs		Q9BWT3	P61457
PDB IDs		4LT6
Enriched GO Terms of Interacting Partners?
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