VPS52 and TPM3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		VPS52	TPM3
Description		VPS52 subunit of GARP complex	tropomyosin 3
Image		No pdb structure
GO Annotations	Cellular Component	GARP Complex Golgi Apparatus Cytosol Endosome Membrane Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Recycling Endosome EARP Complex	Stress Fiber Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Actin Filament Actin Cytoskeleton Extracellular Exosome
	Molecular Function	Protein Binding Rab GTPase Binding Syntaxin Binding	Molecular_function Protein Binding Actin Filament Binding
	Biological Process	Golgi To Vacuole Transport Lysosomal Transport Ectodermal Cell Differentiation Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Embryonic Ectodermal Digestive Tract Development	Muscle Contraction Actin Filament Organization Muscle Filament Sliding
Pathways		Retrograde transport at the Trans-Golgi-Network	Striated Muscle Contraction Smooth Muscle Contraction
Drugs			Phenethyl Isothiocyanate
Diseases			Congenital fiber type disproportion (CFTD) Cap myopathy Thyroid cancer Nemaline myopathy
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971)	Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Platelet count ( 27863252) Smoking initiation (ever regular vs never regular) ( 30679032)
Interacting Genes		50 interacting genes: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EEF1AKNMT EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 HGS KANK2 KIAA1217 KIF5B KLC3 LMO4 MAGEL2 MAPK3 MFAP1 MRPL11 NFKBIB NOP2 PIMREG PPP1R18 PRKAA1 PRKAA2 RAB4A RABEP2 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS53 WTAP ZMAT2	44 interacting genes: ACTA1 ACTB BLOC1S6 C1orf216 CCDC102B CCDC114 CCDC146 CCHCR1 CNN1 DVL2 FAM9C FBXO5 HDDC3 HOOK2 HSF2 IFIT3 IKBIP KCNE1 KIFC3 KXD1 LCA5L LURAP1 MAD1L1 MAGEA11 NEK2 NOD2 OIP5 PBX3 S100A2 S100A4 SMAD3 SUMO4 SYCE1 TFPT THAP1 TLK1 TMOD1 TMOD2 TNNT1 TRAP1 TRIM27 TRIP6 VPS52 WASH3P
Entrez ID		6293	7170
HPRD ID		09142	01840
Ensembl ID		ENSG00000223501	ENSG00000143549
Uniprot IDs		A0A1U9X8S4 B3KMF7 B4DS44 Q4VXZ2 Q8N1B4	A0A087WWU8 A0A0S2Z4G4 A0A0S2Z4I4 B4DQ80 P06753
PDB IDs			6OTN
Enriched GO Terms of Interacting Partners?
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