QARS1 and DUSP11

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		QARS1	DUSP11
Description		glutaminyl-tRNA synthetase 1	dual specificity phosphatase 11
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrial Matrix Cytosol Aminoacyl-tRNA Synthetase Multienzyme Complex Protein-containing Complex	Fibrillar Center Nucleus Nucleoplasm Nuclear Speck Intercellular Bridge
	Molecular Function	Glutamine-tRNA Ligase Activity Protein Kinase Inhibitor Activity Protein Binding ATP Binding Protein Kinase Binding	RNA Binding Polynucleotide 5'-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity Nucleotide Phosphatase Activity, Acting On Free Nucleotides
	Biological Process	TRNA Aminoacylation For Protein Translation Glutaminyl-tRNA Aminoacylation Negative Regulation Of Protein Kinase Activity Brain Development Negative Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Apoptotic Signaling Pathway	RNA Processing Protein Dephosphorylation RNA Metabolic Process Peptidyl-tyrosine Dephosphorylation Polynucleotide 5' Dephosphorylation
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation Mitochondrial tRNA aminoacylation
Drugs
Diseases
GWAS			Creatinine levels ( 20383145) Lean body mass ( 28552196) Metabolite levels ( 21931564) Serum metabolite levels ( 23093944)
Interacting Genes		39 interacting genes: ACTN2 ANXA7 APP ASL CDK4 CDKN1A CLTC CPNE3 DPPA4 DTX2 DUSP11 FAM118B GADD45A GSK3B H2AX IRF1 KCNE3 KLC3 LAMTOR3 LZTS2 MAP3K5 NLGN3 PIK3R3 PIN1 PRRC2A RARS1 RNF11 SMAD9 SMN1 STK3 TCF12 TK1 TLE5 TRAF2 TRAF4 TRIP13 TSC22D1 TTR VPS37B	3 interacting genes: QARS1 SRSF7 SRSF9
Entrez ID		5859	8446
HPRD ID		07223	04368
Ensembl ID		ENSG00000172053	ENSG00000144048
Uniprot IDs		B7Z840 P47897	O75319
PDB IDs		4R3Z 4YE6 4YE8 4YE9	4JMJ 4MBB 4NYH
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?