QARS1 and RARS1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (biochemical, affinity chromatography technology)
HPRD (in vitro)

		QARS1	RARS1
Description		glutaminyl-tRNA synthetase 1	arginyl-tRNA synthetase 1
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GO Annotations	Cellular Component	Cytoplasm Mitochondrial Matrix Cytosol Aminoacyl-tRNA Synthetase Multienzyme Complex Protein-containing Complex	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex Extracellular Exosome
	Molecular Function	Glutamine-tRNA Ligase Activity Protein Kinase Inhibitor Activity Protein Binding ATP Binding Protein Kinase Binding	TRNA Binding Arginine-tRNA Ligase Activity Protein Binding ATP Binding Arginine Binding Cadherin Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Glutaminyl-tRNA Aminoacylation Negative Regulation Of Protein Kinase Activity Brain Development Negative Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Apoptotic Signaling Pathway	TRNA Aminoacylation For Protein Translation Arginyl-tRNA Aminoacylation
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation Mitochondrial tRNA aminoacylation	Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs
Diseases
GWAS
Interacting Genes		39 interacting genes: ACTN2 ANXA7 APP ASL CDK4 CDKN1A CLTC CPNE3 DPPA4 DTX2 DUSP11 FAM118B GADD45A GSK3B H2AX IRF1 KCNE3 KLC3 LAMTOR3 LZTS2 MAP3K5 NLGN3 PIK3R3 PIN1 PRRC2A RARS1 RNF11 SMAD9 SMN1 STK3 TCF12 TK1 TLE5 TRAF2 TRAF4 TRIP13 TSC22D1 TTR VPS37B	3 interacting genes: AIMP1 EPRS1 QARS1
Entrez ID		5859	5917
HPRD ID		07223	00142
Ensembl ID		ENSG00000172053	ENSG00000113643
Uniprot IDs		B7Z840 P47897	P54136
PDB IDs		4R3Z 4YE6 4YE8 4YE9	4Q2T 4Q2X 4Q2Y 4R3Z 4ZAJ
Enriched GO Terms of Interacting Partners?
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