VARS2 and MAL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		VARS2	MAL2
Description		valyl-tRNA synthetase 2, mitochondrial	mal, T cell differentiation protein 2 (gene/pseudogene)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol	Endomembrane System Integral Component Of Membrane Apical Plasma Membrane Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Aminoacyl-tRNA Editing Activity Valine-tRNA Ligase Activity ATP Binding	Protein Binding Structural Constituent Of Myelin Sheath
	Biological Process	TRNA Aminoacylation For Protein Translation Valyl-tRNA Aminoacylation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity	Myelination Transcytosis
Pathways		Mitochondrial tRNA aminoacylation
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Conotruncal heart defects (maternal effects) ( 28468790) Gestational age at birth (maternal effect) ( 28877031) HIV-1 control ( 20041166) Microalbuminuria in type 1 diabetes ( 31537649) Pubertal anthropometrics ( 23449627) Squamous cell lung carcinoma ( 28604730) Ulcerative colitis ( 20848476) Urate levels ( 31578528)	Blood pressure (smoking interaction) ( 25189868) Gallstone disease ( 30504769) Hippocampal atrophy ( 19668339) Osteoprotegerin levels ( 25080503)
Interacting Genes		6 interacting genes: ABI2 CMTM5 MAL2 NCK2 PIK3CA SORBS3	21 interacting genes: ABCG8 ARFIP2 CREB3 FAM3A GAD1 GAD2 NDRG4 PBX3 PIMREG PPP1CA PTPN9 RAB37 S100B SH3GL1 SHMT2 TBRG4 TPD52 TPD52L1 TPD52L2 TUBB VARS2
Entrez ID		57176	114569
HPRD ID		11670	14351
Ensembl ID		ENSG00000137411	ENSG00000147676
Uniprot IDs		A0A1U9X9B3 B4DG77 B4E0K6 Q5ST30	A0A024R9E4 Q969L2
PDB IDs
Enriched GO Terms of Interacting Partners?
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