MAL2 and NDRG4

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		MAL2	NDRG4
Description		mal, T cell differentiation protein 2 (gene/pseudogene)	NDRG family member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endomembrane System Integral Component Of Membrane Apical Plasma Membrane Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome	Cytoplasm Mitochondrion Endoplasmic Reticulum Membrane Cytosol Basolateral Plasma Membrane Cell Projection Membrane
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath	Molecular_function Protein Binding
	Biological Process	Myelination Transcytosis	Heart Looping Signal Transduction Brain Development Visual Learning Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Projection Development Negative Regulation Of Smooth Muscle Cell Migration Cell Differentiation Embryonic Heart Tube Development Vesicle Docking Negative Regulation Of Smooth Muscle Cell Proliferation Cardiac Muscle Cell Proliferation Cell Migration Involved In Heart Development Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Endocytic Recycling
Pathways
Drugs
Diseases
GWAS		Blood pressure (smoking interaction) ( 25189868) Gallstone disease ( 30504769) Hippocampal atrophy ( 19668339) Osteoprotegerin levels ( 25080503)	Electrocardiographic traits ( 20062063) QT interval ( 22726844 19305408 19305409) Schizophrenia ( 29483656)
Interacting Genes		21 interacting genes: ABCG8 ARFIP2 CREB3 FAM3A GAD1 GAD2 NDRG4 PBX3 PIMREG PPP1CA PTPN9 RAB37 S100B SH3GL1 SHMT2 TBRG4 TPD52 TPD52L1 TPD52L2 TUBB VARS2	6 interacting genes: AGTRAP ARL6IP1 CMTM5 MAL2 REEP6 RTN3
Entrez ID		114569	65009
HPRD ID		14351	14817
Ensembl ID		ENSG00000147676	ENSG00000103034
Uniprot IDs		A0A024R9E4 Q969L2	A0A024R6V8 A0A0S2Z5L7 A0A0S2Z5R7 B7Z9X4 Q9ULP0
PDB IDs
Enriched GO Terms of Interacting Partners?
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