MAL2 and PTPN9

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MAL2	PTPN9
Description		mal, T cell differentiation protein 2 (gene/pseudogene)	protein tyrosine phosphatase non-receptor type 9
Image		No pdb structure
GO Annotations	Cellular Component	Endomembrane System Integral Component Of Membrane Apical Plasma Membrane Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleoplasm Cytoplasm Neuron Projection Terminus
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Myelination Transcytosis	Protein Dephosphorylation Negative Regulation Of Neuron Projection Development Peptidyl-tyrosine Dephosphorylation Cellular Response To Cytokine Stimulus Positive Regulation Of Protein Localization To Plasma Membrane
Pathways			Interleukin-37 signaling
Drugs
Diseases
GWAS		Blood pressure (smoking interaction) ( 25189868) Gallstone disease ( 30504769) Hippocampal atrophy ( 19668339) Osteoprotegerin levels ( 25080503)	Estimated glomerular filtration rate ( 31015462) Height ( 25429064 31562340 20189936) Type 2 diabetes ( 30297969)
Interacting Genes		21 interacting genes: ABCG8 ARFIP2 CREB3 FAM3A GAD1 GAD2 NDRG4 PBX3 PIMREG PPP1CA PTPN9 RAB37 S100B SH3GL1 SHMT2 TBRG4 TPD52 TPD52L1 TPD52L2 TUBB VARS2	10 interacting genes: AGTRAP CMTM5 CREB3 GHR LMNA MAL2 NSF REEP6 RTN3 STX6
Entrez ID		114569	5780
HPRD ID		14351	02864
Ensembl ID		ENSG00000147676	ENSG00000169410
Uniprot IDs		A0A024R9E4 Q969L2	P43378 Q6IQ43
PDB IDs			2PA5 4GE2 4GE5 4GE6 4ICZ
Enriched GO Terms of Interacting Partners?
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