MAL2 and VARS2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MAL2	VARS2
Description		mal, T cell differentiation protein 2 (gene/pseudogene)	valyl-tRNA synthetase 2, mitochondrial
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endomembrane System Integral Component Of Membrane Apical Plasma Membrane Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome	Mitochondrion Cytosol
	Molecular Function	Protein Binding Structural Constituent Of Myelin Sheath	Aminoacyl-tRNA Editing Activity Valine-tRNA Ligase Activity ATP Binding
	Biological Process	Myelination Transcytosis	TRNA Aminoacylation For Protein Translation Valyl-tRNA Aminoacylation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity
Pathways			Mitochondrial tRNA aminoacylation
Drugs
Diseases
GWAS		Blood pressure (smoking interaction) ( 25189868) Gallstone disease ( 30504769) Hippocampal atrophy ( 19668339) Osteoprotegerin levels ( 25080503)	Autism spectrum disorder or schizophrenia ( 28540026) Conotruncal heart defects (maternal effects) ( 28468790) Gestational age at birth (maternal effect) ( 28877031) HIV-1 control ( 20041166) Microalbuminuria in type 1 diabetes ( 31537649) Pubertal anthropometrics ( 23449627) Squamous cell lung carcinoma ( 28604730) Ulcerative colitis ( 20848476) Urate levels ( 31578528)
Interacting Genes		21 interacting genes: ABCG8 ARFIP2 CREB3 FAM3A GAD1 GAD2 NDRG4 PBX3 PIMREG PPP1CA PTPN9 RAB37 S100B SH3GL1 SHMT2 TBRG4 TPD52 TPD52L1 TPD52L2 TUBB VARS2	6 interacting genes: ABI2 CMTM5 MAL2 NCK2 PIK3CA SORBS3
Entrez ID		114569	57176
HPRD ID		14351	11670
Ensembl ID		ENSG00000147676	ENSG00000137411
Uniprot IDs		A0A024R9E4 Q969L2	A0A1U9X9B3 B4DG77 B4E0K6 Q5ST30
PDB IDs
Enriched GO Terms of Interacting Partners?
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