XRCC4 and BIN1

  • Number of citations of the paper that reports this interaction (PubMedID 16275660)
  • 16
  • Data Source:
  • BioGRID (unspecified method, pull down, two hybrid)
  • HPRD (in vitro, in vivo, two hybrid)

XRCC4

BIN1

Description X-ray repair cross complementing 4 bridging integrator 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Clozapine-induced agranulocytosis ( 25187353)
  • Diisocyanate-induced asthma ( 25918132)
  • Heel bone mineral density ( 30598549)
  • Osteoarthritis biomarkers ( 25057126)
  • Squamous cell lung carcinoma ( 28604730)
  • Type 2 diabetes ( 25760438)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • White matter integrity (fractional anisotropy) ( 29752348)
  • White matter integrity (mean diffusivity) ( 29752348)
Interacting Genes 19 interacting genes: ACTN1 AHNAK APLF APTX ASTE1 BIN1 CAAP1 CALM1 CHD3 CSNK2A1 FAM9B GZMB IFFO1 LIG4 NBN NHEJ1 PNKP PRKDC VIM 43 interacting genes: ABL1 ACTA1 ACTG1 AMPH AP2A1 AP2A2 APP ASAP2 ATXN2 CLIP1 CUX1 DLGAP4 DNM1 DNM2 E2F1 FBP1 FHL2 ITCH ITGA1 ITGA3 ITGA6 MAP4K3 MBNL1 MYC PLD1 PLD2 PTK2 RAP1A RFX3 RIN2 RIN3 SH3GL2 SH3GLB1 SNX4 SOS1 SOS2 SYN1 SYNJ1 TP73 UBC WASL XRCC4 ZBTB3
Entrez ID 7518 274
HPRD ID 15951 03150
Ensembl ID ENSG00000152422 ENSG00000136717
Uniprot IDs A0A024RAL0 A0A024RAP0 A0A024RAQ8 Q13426 Q7Z763 A0A024RAE9 A0A024RAF0 A0A024RAF1 A0A024RAF6 A0A024RAG8 A0A024RAG9 A0A024RAI4 A0A024RAI5 A0A024RAI6 A0A024RAJ2 A0A024RAJ3 B7Z2Z2 B7Z6Y2 O00499 Q9BTH3
PDB IDs 1FU1 1IK9 3II6 3MUD 3Q4F 3RWR 3SR2 3W03 4XA4 5CHX 5CJ0 5CJ4 5E50 5WJ7 5WLZ 6ABO 1MUZ 1MV0 1MV3 2FIC 2RMY 2RND 5I22
Enriched GO Terms of Interacting Partners?
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