PPP1CB and AATK

Number of citations of the paper that reports this interaction (PubMedID 28065597)
26

Data Source:
BioGRID (two hybrid)

		PPP1CB	AATK
Description		protein phosphatase 1 catalytic subunit beta	apoptosis associated tyrosine kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Protein Phosphatase Type 1 Complex Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Glycogen Granule Extracellular Exosome PTW/PP1 Phosphatase Complex	Cellular_component Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding Phosphatase Activity Myosin Phosphatase Activity Protein Kinase Binding Metal Ion Binding Myosin-light-chain-phosphatase Activity	Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Glycogen Metabolic Process Regulation Of Glycogen Biosynthetic Process Regulation Of Glycogen Catabolic Process Protein Dephosphorylation Regulation Of Cell Adhesion Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Cell Division	Biological_process Peptidyl-tyrosine Phosphorylation
Pathways		Triglyceride catabolism Downregulation of TGF-beta receptor signaling Regulation of PLK1 Activity at G2/M Transition Circadian Clock RHO GTPases activate PKNs RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs
Diseases
GWAS		Body mass index ( 25673413) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Excessive sweating ( 29895819) Heel bone mineral density ( 30598549 28869591) Pre-treatment viral load in HIV-1 infection ( 31219150) Pure non-grapefruit juice consumption ( 31046077)	Neuroticism ( 29255261) Obesity-related traits ( 23251661) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		30 interacting genes: AATK ACTN2 AURKA BRCA1 CLK1 CLOCK CSNK2B CSRNP2 DELEC1 FBXO7 H3-3A H3C1 LMTK2 MAPT NONO PPP1R12B PPP1R12C PPP1R16A PPP1R16B PPP1R2B PPP1R9B PPP2R5C PRKAR2A PTK2 RB1 RORC SH2D4A TLX1 WBP11 ZFYVE9	40 interacting genes: CDC14A CDC25B CDK5 DUPD1 DUSP1 DUSP14 DUSP5 DUSP6 DUSP9 EYA2 EYA4 ILKAP MTMR10 MTMR6 MTMR8 MTMR9 PPM1A PPM1B PPM1F PPM1K PPM1M PPP1CA PPP1CB PPP1CC PPP3CA PPP3CB PTEN PTPDC1 PTPN11 PTPN12 PTPN18 PTPN20 PTPN6 PTPN7 PTPRR SBF1 STK39 STYX TAB1 TPTE2
Entrez ID		5500	9625
HPRD ID		11792	05591
Ensembl ID		ENSG00000213639	ENSG00000181409
Uniprot IDs		P62140 V9HW04	H7C175 Q6ZMQ8
PDB IDs
Enriched GO Terms of Interacting Partners?
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