PPP1CB and WBP11

Number of citations of the paper that reports this interaction (PubMedID 14640981)
16

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		PPP1CB	WBP11
Description		protein phosphatase 1 catalytic subunit beta	WW domain binding protein 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Protein Phosphatase Type 1 Complex Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Glycogen Granule Extracellular Exosome PTW/PP1 Phosphatase Complex	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding Phosphatase Activity Myosin Phosphatase Activity Protein Kinase Binding Metal Ion Binding Myosin-light-chain-phosphatase Activity	Single-stranded DNA Binding RNA Binding Protein Binding WW Domain Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Glycogen Metabolic Process Regulation Of Glycogen Biosynthetic Process Regulation Of Glycogen Catabolic Process Protein Dephosphorylation Regulation Of Cell Adhesion Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Cell Division	MRNA Splicing, Via Spliceosome RRNA Processing MRNA Cis Splicing, Via Spliceosome
Pathways		Triglyceride catabolism Downregulation of TGF-beta receptor signaling Regulation of PLK1 Activity at G2/M Transition Circadian Clock RHO GTPases activate PKNs RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Body mass index ( 25673413) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Excessive sweating ( 29895819) Heel bone mineral density ( 30598549 28869591) Pre-treatment viral load in HIV-1 infection ( 31219150) Pure non-grapefruit juice consumption ( 31046077)
Interacting Genes		30 interacting genes: AATK ACTN2 AURKA BRCA1 CLK1 CLOCK CSNK2B CSRNP2 DELEC1 FBXO7 H3-3A H3C1 LMTK2 MAPT NONO PPP1R12B PPP1R12C PPP1R16A PPP1R16B PPP1R2B PPP1R9B PPP2R5C PRKAR2A PTK2 RB1 RORC SH2D4A TLX1 WBP11 ZFYVE9	29 interacting genes: APBB1 ARF1 C5orf22 CD2BP2 CTNNBL1 DDX17 DDX5 FYN GIGYF2 GRB2 ITSN1 MCRS1 NCK2 NOD2 PIK3R1 PPP1CA PPP1CB PPP1CC PQBP1 PRPF40A RBM5 RTN4IP1 RUNX1T1 SRC TESC TRAF4 TRIP10 VIM WBP4
Entrez ID		5500	51729
HPRD ID		11792	18293
Ensembl ID		ENSG00000213639	ENSG00000084463
Uniprot IDs		P62140 V9HW04	A0A024RAW9 Q9Y2W2
PDB IDs
Enriched GO Terms of Interacting Partners?
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