PPP1CB and PPP1R12B

Number of citations of the paper that reports this interaction (PubMedID 9570949)
17

Data Source:
HPRD (in vitro)

		PPP1CB	PPP1R12B
Description		protein phosphatase 1 catalytic subunit beta	protein phosphatase 1 regulatory subunit 12B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Protein Phosphatase Type 1 Complex Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Glycogen Granule Extracellular Exosome PTW/PP1 Phosphatase Complex	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Z Disc A Band
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding Phosphatase Activity Myosin Phosphatase Activity Protein Kinase Binding Metal Ion Binding Myosin-light-chain-phosphatase Activity	Enzyme Inhibitor Activity Protein Binding Enzyme Activator Activity Phosphatase Regulator Activity Protein Kinase Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Glycogen Metabolic Process Regulation Of Glycogen Biosynthetic Process Regulation Of Glycogen Catabolic Process Protein Dephosphorylation Regulation Of Cell Adhesion Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Cell Division	G2/M Transition Of Mitotic Cell Cycle Regulation Of Muscle Contraction Signal Transduction Positive Regulation Of Catalytic Activity Negative Regulation Of Catalytic Activity
Pathways		Triglyceride catabolism Downregulation of TGF-beta receptor signaling Regulation of PLK1 Activity at G2/M Transition Circadian Clock RHO GTPases activate PKNs RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs	RHO GTPases activate PKNs RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs
Diseases
GWAS		Body mass index ( 25673413) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Excessive sweating ( 29895819) Heel bone mineral density ( 30598549 28869591) Pre-treatment viral load in HIV-1 infection ( 31219150) Pure non-grapefruit juice consumption ( 31046077)	Celiac disease ( 23936387) Coronary heart disease ( 24778558) Obesity-related traits ( 23251661) Sex ratio ( 26763874)
Interacting Genes		30 interacting genes: AATK ACTN2 AURKA BRCA1 CLK1 CLOCK CSNK2B CSRNP2 DELEC1 FBXO7 H3-3A H3C1 LMTK2 MAPT NONO PPP1R12B PPP1R12C PPP1R16A PPP1R16B PPP1R2B PPP1R9B PPP2R5C PRKAR2A PTK2 RB1 RORC SH2D4A TLX1 WBP11 ZFYVE9	3 interacting genes: IL16 PPP1CB PRKG1
Entrez ID		5500	4660
HPRD ID		11792	04794
Ensembl ID		ENSG00000213639	ENSG00000077157
Uniprot IDs		P62140 V9HW04	E1CKY7 O60237
PDB IDs
Enriched GO Terms of Interacting Partners?
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