PPP1CB and CSRNP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PPP1CB	CSRNP2
Description		protein phosphatase 1 catalytic subunit beta	cysteine and serine rich nuclear protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Protein Phosphatase Type 1 Complex Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Glycogen Granule Extracellular Exosome PTW/PP1 Phosphatase Complex	Nuclear Chromatin Nucleus
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding Phosphatase Activity Myosin Phosphatase Activity Protein Kinase Binding Metal Ion Binding Myosin-light-chain-phosphatase Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Phosphatase Binding Sequence-specific DNA Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Glycogen Metabolic Process Regulation Of Glycogen Biosynthetic Process Regulation Of Glycogen Catabolic Process Protein Dephosphorylation Regulation Of Cell Adhesion Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Cell Division	Apoptotic Process Negative Regulation Of Phosphatase Activity Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Triglyceride catabolism Downregulation of TGF-beta receptor signaling Regulation of PLK1 Activity at G2/M Transition Circadian Clock RHO GTPases activate PKNs RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs
Diseases
GWAS		Body mass index ( 25673413) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Excessive sweating ( 29895819) Heel bone mineral density ( 30598549 28869591) Pre-treatment viral load in HIV-1 infection ( 31219150) Pure non-grapefruit juice consumption ( 31046077)
Interacting Genes		30 interacting genes: AATK ACTN2 AURKA BRCA1 CLK1 CLOCK CSNK2B CSRNP2 DELEC1 FBXO7 H3-3A H3C1 LMTK2 MAPT NONO PPP1R12B PPP1R12C PPP1R16A PPP1R16B PPP1R2B PPP1R9B PPP2R5C PRKAR2A PTK2 RB1 RORC SH2D4A TLX1 WBP11 ZFYVE9	3 interacting genes: PPP1CA PPP1CB PPP1CC
Entrez ID		5500	81566
HPRD ID		11792	12608
Ensembl ID		ENSG00000213639	ENSG00000110925
Uniprot IDs		P62140 V9HW04	Q9H175
PDB IDs
Enriched GO Terms of Interacting Partners?
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