PPP1CB and PPP1R16A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid, affinity chromatography technology)

		PPP1CB	PPP1R16A
Description		protein phosphatase 1 catalytic subunit beta	protein phosphatase 1 regulatory subunit 16A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Protein Phosphatase Type 1 Complex Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Glycogen Granule Extracellular Exosome PTW/PP1 Phosphatase Complex	Plasma Membrane
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding Phosphatase Activity Myosin Phosphatase Activity Protein Kinase Binding Metal Ion Binding Myosin-light-chain-phosphatase Activity	Protein Binding Protein Phosphatase Regulator Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Glycogen Metabolic Process Regulation Of Glycogen Biosynthetic Process Regulation Of Glycogen Catabolic Process Protein Dephosphorylation Regulation Of Cell Adhesion Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Cell Division	Regulation Of Phosphoprotein Phosphatase Activity
Pathways		Triglyceride catabolism Downregulation of TGF-beta receptor signaling Regulation of PLK1 Activity at G2/M Transition Circadian Clock RHO GTPases activate PKNs RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs
Drugs
Diseases
GWAS		Body mass index ( 25673413) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Excessive sweating ( 29895819) Heel bone mineral density ( 30598549 28869591) Pre-treatment viral load in HIV-1 infection ( 31219150) Pure non-grapefruit juice consumption ( 31046077)	Age at first birth ( 27798627) Blood metabolite levels ( 26401656) Educational attainment ( 25201988) Height ( 28552196) Mean corpuscular hemoglobin concentration ( 27863252)
Interacting Genes		30 interacting genes: AATK ACTN2 AURKA BRCA1 CLK1 CLOCK CSNK2B CSRNP2 DELEC1 FBXO7 H3-3A H3C1 LMTK2 MAPT NONO PPP1R12B PPP1R12C PPP1R16A PPP1R16B PPP1R2B PPP1R9B PPP2R5C PRKAR2A PTK2 RB1 RORC SH2D4A TLX1 WBP11 ZFYVE9	22 interacting genes: CDH24 DDX27 FSD1 HGS HLA-E IDO1 LY6H LZTS2 PAPSS1 PBDC1 PHPT1 PPP1CA PPP1CB PPP1CC PUF60 RFLNB RGMA TFIP11 TLE5 TPP2 TRIP6 TXNRD1
Entrez ID		5500	84988
HPRD ID		11792	16454
Ensembl ID		ENSG00000213639	ENSG00000160972
Uniprot IDs		P62140 V9HW04	Q96I34
PDB IDs
Enriched GO Terms of Interacting Partners?
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