AATK and PPM1M

Number of citations of the paper that reports this interaction (PubMedID 28065597)
26

Data Source:
BioGRID (two hybrid)

		AATK	PPM1M
Description		apoptosis associated tyrosine kinase	protein phosphatase, Mg2+/Mn2+ dependent 1M
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Nucleus Mitochondrion
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding	Protein Serine/threonine Phosphatase Activity Magnesium-dependent Protein Serine/threonine Phosphatase Activity [pyruvate Dehydrogenase (lipoamide)] Phosphatase Activity Manganese Ion Binding
	Biological Process	Biological_process Peptidyl-tyrosine Phosphorylation	Protein Dephosphorylation Positive Regulation Of Pyruvate Dehydrogenase Activity
Pathways
Drugs
Diseases
GWAS		Neuroticism ( 29255261) Obesity-related traits ( 23251661) Serum uric acid levels in response to allopurinol in gout ( 25676789)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Schizophrenia ( 23974872)
Interacting Genes		40 interacting genes: CDC14A CDC25B CDK5 DUPD1 DUSP1 DUSP14 DUSP5 DUSP6 DUSP9 EYA2 EYA4 ILKAP MTMR10 MTMR6 MTMR8 MTMR9 PPM1A PPM1B PPM1F PPM1K PPM1M PPP1CA PPP1CB PPP1CC PPP3CA PPP3CB PTEN PTPDC1 PTPN11 PTPN12 PTPN18 PTPN20 PTPN6 PTPN7 PTPRR SBF1 STK39 STYX TAB1 TPTE2	2 interacting genes: AATK ERBB3
Entrez ID		9625	132160
HPRD ID		05591	12350
Ensembl ID		ENSG00000181409	ENSG00000164088
Uniprot IDs		H7C175 Q6ZMQ8	B7XGB9 Q96MI6
PDB IDs
Enriched GO Terms of Interacting Partners?
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