PPL and KAZN

Number of citations of the paper that reports this interaction (PubMedID 15337775)
19

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		PPL	KAZN
Description		periplakin	kazrin, periplakin interacting protein
Image			No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Nucleus Cytoplasm Mitochondrion Cytosol Cytoskeleton Intermediate Filament Membrane Desmosome Extracellular Exosome	Cornified Envelope Nucleoplasm Cytosol Cytoskeleton Nuclear Speck Desmosome
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Cadherin Binding	Protein Binding
	Biological Process	Response To Mechanical Stimulus Wound Healing Intermediate Filament Cytoskeleton Organization Cornification	Cornification
Pathways		Formation of the cornified envelope Butyrophilin (BTN) family interactions	Formation of the cornified envelope
Drugs
Diseases
GWAS		Cancer ( 29299148) Diastolic blood pressure ( 28135244 27841878) Height ( 28552196) Lung cancer (asbestos exposure interaction) ( 22637743) Metabolite levels (HVA/MHPG ratio) ( 23319000) Mitochondrial DNA copy number (white blood cells) ( 30704525) Systolic blood pressure ( 27841878)	Body mass index ( 28552196) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Chronotype ( 30696823) Conotruncal heart defects (inherited effects) ( 28468790) Copper levels ( 26025379) Lean body mass ( 28552196) Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321) Mercury levels ( 26025379) Moderate-to-late spontaneous preterm birth ( 31194736) Non-response to antidepressants and depression ( 27622933) Triacylglyceride levels ( 31551469) Urinary albumin-to-creatinine ratio in diabetes ( 31511532) Weight ( 28552196)
Interacting Genes		24 interacting genes: AHCYL1 AKT1 ALAS1 CASP6 CEP57L1 COL17A1 EVPL ITSN1 KAZN KRT8 LARP1 OPRM1 PPHLN1 PTEN RAB3IP RALBP1 SKIL TRAF2 TRIM27 TSC22D4 UBC USP7 VIM ZSCAN1	3 interacting genes: COIL LZTS2 PPL
Entrez ID		5493	23254
HPRD ID		04187	11122
Ensembl ID		ENSG00000118898	ENSG00000189337
Uniprot IDs		O60437	Q674X7
PDB IDs		4Q28
Enriched GO Terms of Interacting Partners?
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