KAZN and PPL

Number of citations of the paper that reports this interaction (PubMedID 15337775)
19

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		KAZN	PPL
Description		kazrin, periplakin interacting protein	periplakin
Image		No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Nucleoplasm Cytosol Cytoskeleton Nuclear Speck Desmosome	Cornified Envelope Nucleus Cytoplasm Mitochondrion Cytosol Cytoskeleton Intermediate Filament Membrane Desmosome Extracellular Exosome
	Molecular Function	Protein Binding	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Cadherin Binding
	Biological Process	Cornification	Response To Mechanical Stimulus Wound Healing Intermediate Filament Cytoskeleton Organization Cornification
Pathways		Formation of the cornified envelope	Formation of the cornified envelope Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS		Body mass index ( 28552196) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Chronotype ( 30696823) Conotruncal heart defects (inherited effects) ( 28468790) Copper levels ( 26025379) Lean body mass ( 28552196) Logical memory (delayed recall) in Alzheimer's disease dementia ( 29274321) Mercury levels ( 26025379) Moderate-to-late spontaneous preterm birth ( 31194736) Non-response to antidepressants and depression ( 27622933) Triacylglyceride levels ( 31551469) Urinary albumin-to-creatinine ratio in diabetes ( 31511532) Weight ( 28552196)	Cancer ( 29299148) Diastolic blood pressure ( 28135244 27841878) Height ( 28552196) Lung cancer (asbestos exposure interaction) ( 22637743) Metabolite levels (HVA/MHPG ratio) ( 23319000) Mitochondrial DNA copy number (white blood cells) ( 30704525) Systolic blood pressure ( 27841878)
Interacting Genes		3 interacting genes: COIL LZTS2 PPL	24 interacting genes: AHCYL1 AKT1 ALAS1 CASP6 CEP57L1 COL17A1 EVPL ITSN1 KAZN KRT8 LARP1 OPRM1 PPHLN1 PTEN RAB3IP RALBP1 SKIL TRAF2 TRIM27 TSC22D4 UBC USP7 VIM ZSCAN1
Entrez ID		23254	5493
HPRD ID		11122	04187
Ensembl ID		ENSG00000189337	ENSG00000118898
Uniprot IDs		Q674X7	O60437
PDB IDs			4Q28
Enriched GO Terms of Interacting Partners?
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