ZNF581 and HMBOX1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZNF581	HMBOX1
Description		zinc finger protein 581	homeobox containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nuclear Chromosome, Telomeric Region Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Cajal Body Nuclear Body PML Body
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded Telomeric DNA Binding Protein Binding Telomeric DNA Binding Identical Protein Binding Sequence-specific DNA Binding Protein-containing Complex Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Telomerase Activity Positive Regulation Of Telomerase Activity
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Interacting Genes		43 interacting genes: APP BANP CALCOCO2 CBY2 CCDC136 CCNDBP1 DAZAP2 DOCK8 DVL2 FSD2 GOLGA2 GOPC HMBOX1 HNRNPC IKZF1 KDM1A KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP4-12 KRTAP4-2 KRTAP5-9 LNX1 LNX2 LZTS2 MDFI MTUS2 NAT14 NOTCH2NLA PDE4DIP PLSCR1 PNMA1 RBPMS SDCBP2 SOX5 SUV39H1 TMCC2 TRAF1 TRAF4 TRIM23 TRIM27	49 interacting genes: ABITRAM AEBP2 APP ATP5PO BYSL C8orf33 CARD9 CBX8 CCNG1 DAB1 DYNLL2 ENTPD2 FAM13C FAM161A FAM74A4 FARS2 FNDC11 FRMD6 FXR2 KAT5 LNX1 MAGEH1 MFAP1 MORF4L1 MRPL11 MRPL28 PIP4K2B PKD1P1 PRKAA1 PRKAA2 RBMY2FP REEP6 RPL9 SAP30L SFR1 SH2D4A SNRPB2 TCEANC UBA6 UBE2Z VPS72 WT1 ZBTB24 ZMAT2 ZNF337 ZNF417 ZNF581 ZNF587 ZNF688
Entrez ID		51545	79618
HPRD ID		15858	07964
Ensembl ID		ENSG00000171425	ENSG00000147421
Uniprot IDs		Q9P0T4	D3DSU2 Q6NT76
PDB IDs			2CUF 4J19
Enriched GO Terms of Interacting Partners?
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