POLR1D and HAX1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		POLR1D	HAX1
Description		RNA polymerase I and III subunit D	HCLS1 associated protein X-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	RNA Polymerase III Complex RNA Polymerase I Complex	P-body Nuclear Envelope Transcription Factor Complex Mitochondrion Mitochondrial Outer Membrane Mitochondrial Intermembrane Space Endoplasmic Reticulum Plasma Membrane Cell Cortex Actin Cytoskeleton Sarcoplasmic Reticulum Lamellipodium Cytoplasmic Vesicle Nuclear Membrane
	Molecular Function	DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Protein Dimerization Activity	Protein Binding Interleukin-1 Binding Protein N-terminus Binding
	Biological Process	Transcription By RNA Polymerase I Transcription By RNA Polymerase III	Mitochondrion Organization Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Actin Filament Polymerization Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Kinase B Signaling Cellular Response To Cytokine Stimulus Regulation Of Autophagy Of Mitochondrion Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Actin Cytoskeleton Reorganization
Pathways		Cytosolic sensors of pathogen-associated DNA NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase III Chain Elongation RNA Polymerase I Transcription Termination RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases		Treacher Collins syndrome	Neutropenic disorders, including the following three diseases: Kostmann syndrome; Cyclic neutropenia; X-linked neutropenia/myelodysplasia
GWAS		Body mass index ( 26426971)	Bipolar disorder ( 31043756) Nicotine dependence ( 28440896) Non-albumin protein levels ( 29403010) Serum total protein level ( 29403010)
Interacting Genes		15 interacting genes: CD3EAP CDC25A CRKL DDIT3 DNAJB4 DNAJB6 E2F4 GRB2 HAX1 MAGEA11 MRPL12 NFKBIB NR3C1 POLR1C PXN	26 interacting genes: ABCB1 ABCB11 ABCB4 BIRC3 CTTN DGKD EIF3F HCLS1 HNF4G IL1A KIAA0513 MAPK10 NEDD4L PKD2 POLR1D PPP3CC PRNP RBX1 RNF217 RPA1 STAT5B SVIL UBAP2L YWHAQ ZNF420 ZNRD1
Entrez ID		51082	10456
HPRD ID		17877	12075
Ensembl ID		ENSG00000186184	ENSG00000143575
Uniprot IDs		A0A087WTY1 P0DPB5 P0DPB6	A0A0S2Z565 A0A0S2Z591 O00165
PDB IDs
Enriched GO Terms of Interacting Partners?
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