POLR1D and DNAJB4

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		POLR1D	DNAJB4
Description		RNA polymerase I and III subunit D	DnaJ heat shock protein family (Hsp40) member B4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	RNA Polymerase III Complex RNA Polymerase I Complex	Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Protein Dimerization Activity	ATPase Activator Activity Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Transcription By RNA Polymerase I Transcription By RNA Polymerase III	Response To Unfolded Protein Response To Heat Positive Regulation Of ATPase Activity Chaperone Cofactor-dependent Protein Refolding
Pathways		Cytosolic sensors of pathogen-associated DNA NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase III Chain Elongation RNA Polymerase I Transcription Termination RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases		Treacher Collins syndrome
GWAS		Body mass index ( 26426971)	Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diastolic blood pressure ( 30224653) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Waist circumference ( 25673412)
Interacting Genes		15 interacting genes: CD3EAP CDC25A CRKL DDIT3 DNAJB4 DNAJB6 E2F4 GRB2 HAX1 MAGEA11 MRPL12 NFKBIB NR3C1 POLR1C PXN	9 interacting genes: HSPA6 MDM2 OPRM1 PABPN1 POLR1D SDIM1 SMAD3 TBL1X TBPL2
Entrez ID		51082	11080
HPRD ID		17877	07486
Ensembl ID		ENSG00000186184	ENSG00000162616
Uniprot IDs		A0A087WTY1 P0DPB5 P0DPB6	B4DNN2 Q9UDY4
PDB IDs
Enriched GO Terms of Interacting Partners?
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