HAX1 and KIAA0513

Number of citations of the paper that reports this interaction (PubMedID 17010949)
7

Data Source:
HPRD (two hybrid)

		HAX1	KIAA0513
Description		HCLS1 associated protein X-1	KIAA0513
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	P-body Nuclear Envelope Transcription Factor Complex Mitochondrion Mitochondrial Outer Membrane Mitochondrial Intermembrane Space Endoplasmic Reticulum Plasma Membrane Cell Cortex Actin Cytoskeleton Sarcoplasmic Reticulum Lamellipodium Cytoplasmic Vesicle Nuclear Membrane	Cytoplasm
	Molecular Function	Protein Binding Interleukin-1 Binding Protein N-terminus Binding
	Biological Process	Mitochondrion Organization Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Actin Filament Polymerization Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Kinase B Signaling Cellular Response To Cytokine Stimulus Regulation Of Autophagy Of Mitochondrion Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Actin Cytoskeleton Reorganization
Pathways
Drugs
Diseases		Neutropenic disorders, including the following three diseases: Kostmann syndrome; Cyclic neutropenia; X-linked neutropenia/myelodysplasia
GWAS		Bipolar disorder ( 31043756) Nicotine dependence ( 28440896) Non-albumin protein levels ( 29403010) Serum total protein level ( 29403010)	Amyotrophic lateral sclerosis ( 22959728) Dysphagia ( 26116289) Lateral ventricle temporal horn volume ( 31530798)
Interacting Genes		26 interacting genes: ABCB1 ABCB11 ABCB4 BIRC3 CTTN DGKD EIF3F HCLS1 HNF4G IL1A KIAA0513 MAPK10 NEDD4L PKD2 POLR1D PPP3CC PRNP RBX1 RNF217 RPA1 STAT5B SVIL UBAP2L YWHAQ ZNF420 ZNRD1	4 interacting genes: APP HAX1 INTS4 WWC1
Entrez ID		10456	9764
HPRD ID		12075	17192
Ensembl ID		ENSG00000143575	ENSG00000135709
Uniprot IDs		A0A0S2Z565 A0A0S2Z591 O00165	O60268
PDB IDs
Enriched GO Terms of Interacting Partners?
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