POLR1D and DNAJB6

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		POLR1D	DNAJB6
Description		RNA polymerase I and III subunit D	DnaJ heat shock protein family (Hsp40) member B6
Image		No pdb structure
GO Annotations	Cellular Component	RNA Polymerase III Complex RNA Polymerase I Complex	Nucleus Nucleoplasm Cytosol Membrane Z Disc Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Protein Dimerization Activity	ATPase Activator Activity DNA Binding Protein Binding Heat Shock Protein Binding Unfolded Protein Binding Chaperone Binding
	Biological Process	Transcription By RNA Polymerase I Transcription By RNA Polymerase III	Protein Folding Actin Cytoskeleton Organization Extracellular Matrix Organization Positive Regulation Of ATPase Activity Regulation Of Protein Localization Protein Localization To Nucleus Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Intermediate Filament Organization Negative Regulation Of Transcription, DNA-templated Chorio-allantoic Fusion Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Chorion Development Negative Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat
Pathways		Cytosolic sensors of pathogen-associated DNA NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase III Chain Elongation RNA Polymerase I Transcription Termination RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter	Regulation of HSF1-mediated heat shock response
Drugs
Diseases		Treacher Collins syndrome
GWAS		Body mass index ( 26426971)	Body mass index ( 28552196) Waist circumference ( 28552196)
Interacting Genes		15 interacting genes: CD3EAP CDC25A CRKL DDIT3 DNAJB4 DNAJB6 E2F4 GRB2 HAX1 MAGEA11 MRPL12 NFKBIB NR3C1 POLR1C PXN	7 interacting genes: APP BRMS1 KRT18 MAP3K1 PIK3CA POLR1D USP8
Entrez ID		51082	10049
HPRD ID		17877	07107
Ensembl ID		ENSG00000186184	ENSG00000105993
Uniprot IDs		A0A087WTY1 P0DPB5 P0DPB6	A0A0J9YX62 O75190
PDB IDs			6U3R 6U3S
Enriched GO Terms of Interacting Partners?
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