TBC1D25 and GABARAPL2

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (pull down, affinity chromatography technology)

		TBC1D25	GABARAPL2
Description		TBC1 domain family member 25	GABA type A receptor associated protein like 2
Image		No pdb structure
GO Annotations	Cellular Component	Autophagosome Cytoplasmic Vesicle	Golgi Membrane Autophagosome Membrane Intracellular Cytoplasm Autophagosome Golgi Apparatus Cytosol Cytoplasmic Vesicle
	Molecular Function	GTPase Activator Activity Protein Binding Rab GTPase Binding	SNARE Binding Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding ATPase Binding
	Biological Process	Intracellular Protein Transport Autophagy Activation Of GTPase Activity Regulation Of Autophagosome Maturation	Autophagosome Assembly Autophagy Of Mitochondrion Intra-Golgi Vesicle-mediated Transport Autophagy Cellular Response To Nitrogen Starvation Protein Transport Macroautophagy Positive Regulation Of ATPase Activity Autophagosome Maturation Negative Regulation Of Proteasomal Protein Catabolic Process
Pathways		TBC/RABGAPs	Macroautophagy TBC/RABGAPs
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Pancreatic cancer ( 25086665)
Interacting Genes		8 interacting genes: FEZ1 FEZ2 GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B RAB2A	66 interacting genes: AAMP AGTRAP AHNAK2 AMBRA1 ANK2 APP ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4D ATG7 BCL2L13 CALCOCO1 CALCOCO2 CLN8 CUL3 EGFR FUNDC1 GIMAP6 GOSR1 GPR37 KASH5 KBTBD6 KBTBD7 KIAA1958 KLHL5 KRTAP10-7 KRTAP10-9 LRSAM1 MAP1LC3B MCPH1 MEFV MLX NBR1 NEDD4 NSF OPTN OSBPL7 PRKAR2A PTPRA RAP1A RAP2A RB1CC1 RCN2 RPS2 SGTA SIK2 SQSTM1 TAX1BP1 TBC1D25 TBC1D5 TBC1D9 TBC1D9B TNIP1 TP53INP1 TP53INP2 TRIM21 TSR2 UBA5 ULK1 ULK2 VDR WDFY3 YWHAZ
Entrez ID		4943	11345
HPRD ID		08948	16246
Ensembl ID		ENSG00000068354	ENSG00000034713
Uniprot IDs		B4DF03 Q3MII6	P60520
PDB IDs			4CO7
Enriched GO Terms of Interacting Partners?
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