GABARAPL2 and TBC1D5

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		GABARAPL2	TBC1D5
Description		GABA type A receptor associated protein like 2	TBC1 domain family member 5
Image
GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Intracellular Cytoplasm Autophagosome Golgi Apparatus Cytosol Cytoplasmic Vesicle	Autophagosome Golgi Apparatus Cytosol Endosome Membrane AP-2 Adaptor Complex Retromer Complex Intracellular Membrane-bounded Organelle Atg1/ULK1 Kinase Complex
	Molecular Function	SNARE Binding Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding ATPase Binding	GTPase Activator Activity Protein Binding Rab GTPase Binding AP-2 Adaptor Complex Binding Protein-containing Complex Binding Retromer Complex Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Intra-Golgi Vesicle-mediated Transport Autophagy Cellular Response To Nitrogen Starvation Protein Transport Macroautophagy Positive Regulation Of ATPase Activity Autophagosome Maturation Negative Regulation Of Proteasomal Protein Catabolic Process	Positive Regulation Of Receptor Internalization Intracellular Protein Transport Autophagy Macroautophagy Retrograde Transport, Endosome To Golgi Response To Starvation Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		Macroautophagy TBC/RABGAPs
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Pancreatic cancer ( 25086665)	General risk tolerance (MTAG) ( 30643258) Height ( 28552196) Mean platelet volume ( 27863252) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Platelet count ( 27863252) Platelet distribution width ( 27863252) Plateletcrit ( 27863252) Schizophrenia ( 28991256 25056061 29483656) Self-reported risk-taking behaviour ( 30271922)
Interacting Genes		66 interacting genes: AAMP AGTRAP AHNAK2 AMBRA1 ANK2 APP ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4D ATG7 BCL2L13 CALCOCO1 CALCOCO2 CLN8 CUL3 EGFR FUNDC1 GIMAP6 GOSR1 GPR37 KASH5 KBTBD6 KBTBD7 KIAA1958 KLHL5 KRTAP10-7 KRTAP10-9 LRSAM1 MAP1LC3B MCPH1 MEFV MLX NBR1 NEDD4 NSF OPTN OSBPL7 PRKAR2A PTPRA RAP1A RAP2A RB1CC1 RCN2 RPS2 SGTA SIK2 SQSTM1 TAX1BP1 TBC1D25 TBC1D5 TBC1D9 TBC1D9B TNIP1 TP53INP1 TP53INP2 TRIM21 TSR2 UBA5 ULK1 ULK2 VDR WDFY3 YWHAZ	7 interacting genes: AP2M1 ATXN1 EIF1AD GABARAPL1 GABARAPL2 MAP1LC3A UBC
Entrez ID		11345	9779
HPRD ID		16246	10262
Ensembl ID		ENSG00000034713	ENSG00000131374
Uniprot IDs		P60520	B9A6K1 Q92609
PDB IDs		4CO7	5GTU
Enriched GO Terms of Interacting Partners?
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