GABARAPL2 and TBC1D25

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (pull down, affinity chromatography technology)

		GABARAPL2	TBC1D25
Description		GABA type A receptor associated protein like 2	TBC1 domain family member 25
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Intracellular Cytoplasm Autophagosome Golgi Apparatus Cytosol Cytoplasmic Vesicle	Autophagosome Cytoplasmic Vesicle
	Molecular Function	SNARE Binding Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding ATPase Binding	GTPase Activator Activity Protein Binding Rab GTPase Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Intra-Golgi Vesicle-mediated Transport Autophagy Cellular Response To Nitrogen Starvation Protein Transport Macroautophagy Positive Regulation Of ATPase Activity Autophagosome Maturation Negative Regulation Of Proteasomal Protein Catabolic Process	Intracellular Protein Transport Autophagy Activation Of GTPase Activity Regulation Of Autophagosome Maturation
Pathways		Macroautophagy TBC/RABGAPs	TBC/RABGAPs
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Pancreatic cancer ( 25086665)
Interacting Genes		66 interacting genes: AAMP AGTRAP AHNAK2 AMBRA1 ANK2 APP ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4D ATG7 BCL2L13 CALCOCO1 CALCOCO2 CLN8 CUL3 EGFR FUNDC1 GIMAP6 GOSR1 GPR37 KASH5 KBTBD6 KBTBD7 KIAA1958 KLHL5 KRTAP10-7 KRTAP10-9 LRSAM1 MAP1LC3B MCPH1 MEFV MLX NBR1 NEDD4 NSF OPTN OSBPL7 PRKAR2A PTPRA RAP1A RAP2A RB1CC1 RCN2 RPS2 SGTA SIK2 SQSTM1 TAX1BP1 TBC1D25 TBC1D5 TBC1D9 TBC1D9B TNIP1 TP53INP1 TP53INP2 TRIM21 TSR2 UBA5 ULK1 ULK2 VDR WDFY3 YWHAZ	8 interacting genes: FEZ1 FEZ2 GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B RAB2A
Entrez ID		11345	4943
HPRD ID		16246	08948
Ensembl ID		ENSG00000034713	ENSG00000068354
Uniprot IDs		P60520	B4DF03 Q3MII6
PDB IDs		4CO7
Enriched GO Terms of Interacting Partners?
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