GABARAPL2 and WDFY3

Number of citations of the paper that reports this interaction (PubMedID 24668264)
39

Data Source:
BioGRID (affinity chromatography technology, pull down)

		GABARAPL2	WDFY3
Description		GABA type A receptor associated protein like 2	WD repeat and FYVE domain containing 3
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GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Intracellular Cytoplasm Autophagosome Golgi Apparatus Cytosol Cytoplasmic Vesicle	Nuclear Envelope Nucleoplasm Nucleolus Cytoplasm Autophagosome Cytosol Plasma Membrane Inclusion Body PML Body Extrinsic Component Of Membrane Axon Nuclear Membrane Atg12-Atg5-Atg16 Complex Perikaryon Extrinsic Component Of Autophagosome Membrane
	Molecular Function	SNARE Binding Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding ATPase Binding	Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity Protein Binding 1-phosphatidylinositol Binding Metal Ion Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Intra-Golgi Vesicle-mediated Transport Autophagy Cellular Response To Nitrogen Starvation Protein Transport Macroautophagy Positive Regulation Of ATPase Activity Autophagosome Maturation Negative Regulation Of Proteasomal Protein Catabolic Process	Multicellular Organism Development Aggrephagy
Pathways		Macroautophagy TBC/RABGAPs
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Pancreatic cancer ( 25086665)	Cerebral amyloid deposition (PET imaging) ( 26252872) Oropharynx cancer ( 27749845)
Interacting Genes		66 interacting genes: AAMP AGTRAP AHNAK2 AMBRA1 ANK2 APP ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4D ATG7 BCL2L13 CALCOCO1 CALCOCO2 CLN8 CUL3 EGFR FUNDC1 GIMAP6 GOSR1 GPR37 KASH5 KBTBD6 KBTBD7 KIAA1958 KLHL5 KRTAP10-7 KRTAP10-9 LRSAM1 MAP1LC3B MCPH1 MEFV MLX NBR1 NEDD4 NSF OPTN OSBPL7 PRKAR2A PTPRA RAP1A RAP2A RB1CC1 RCN2 RPS2 SGTA SIK2 SQSTM1 TAX1BP1 TBC1D25 TBC1D5 TBC1D9 TBC1D9B TNIP1 TP53INP1 TP53INP2 TRIM21 TSR2 UBA5 ULK1 ULK2 VDR WDFY3 YWHAZ	15 interacting genes: ATG5 CEP76 GABARAPL1 GABARAPL2 GRB2 MAP1LC3C MDFI PRMT1 PRMT6 RABGAP1L STAT3 SUV39H1 TNS2 TRIM39 ZBTB44
Entrez ID		11345	23001
HPRD ID		16246	10304
Ensembl ID		ENSG00000034713	ENSG00000163625
Uniprot IDs		P60520	A0A024RDC2 Q8IZQ1
PDB IDs		4CO7	3WIM
Enriched GO Terms of Interacting Partners?
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