GABARAPL2 and NBR1

Number of citations of the paper that reports this interaction (PubMedID 20562859)
598

Data Source:
BioGRID (affinity chromatography technology, two hybrid, affinity chromatography technology)

		GABARAPL2	NBR1
Description		GABA type A receptor associated protein like 2	NBR1 autophagy cargo receptor
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GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Intracellular Cytoplasm Autophagosome Golgi Apparatus Cytosol Cytoplasmic Vesicle	Phagophore Assembly Site Nucleoplasm Mitochondrion Lysosome Late Endosome Autophagosome Cytosol Membrane Nuclear Body M Band Intracellular Membrane-bounded Organelle Receptor Complex
	Molecular Function	SNARE Binding Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding ATPase Binding	Protein Binding Zinc Ion Binding Ubiquitin Binding Mitogen-activated Protein Kinase Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion Intra-Golgi Vesicle-mediated Transport Autophagy Cellular Response To Nitrogen Starvation Protein Transport Macroautophagy Positive Regulation Of ATPase Activity Autophagosome Maturation Negative Regulation Of Proteasomal Protein Catabolic Process	Macroautophagy Regulation Of Bone Mineralization Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Osteoblast Differentiation
Pathways		Macroautophagy TBC/RABGAPs	Pexophagy Pexophagy
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Pancreatic cancer ( 25086665)
Interacting Genes		66 interacting genes: AAMP AGTRAP AHNAK2 AMBRA1 ANK2 APP ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4D ATG7 BCL2L13 CALCOCO1 CALCOCO2 CLN8 CUL3 EGFR FUNDC1 GIMAP6 GOSR1 GPR37 KASH5 KBTBD6 KBTBD7 KIAA1958 KLHL5 KRTAP10-7 KRTAP10-9 LRSAM1 MAP1LC3B MCPH1 MEFV MLX NBR1 NEDD4 NSF OPTN OSBPL7 PRKAR2A PTPRA RAP1A RAP2A RB1CC1 RCN2 RPS2 SGTA SIK2 SQSTM1 TAX1BP1 TBC1D25 TBC1D5 TBC1D9 TBC1D9B TNIP1 TP53INP1 TP53INP2 TRIM21 TSR2 UBA5 ULK1 ULK2 VDR WDFY3 YWHAZ	21 interacting genes: ATXN1L AXIN1 CALM1 CIB1 FEZ1 GABARAP GABARAPL2 GSK3A GSK3B ITSN2 MAP1LC3A MAP1LC3B MAP2K4 SQSTM1 SYT4 TTN UBC UBE2D2 UBE2D3 USP8 VTA1
Entrez ID		11345	4077
HPRD ID		16246	01326
Ensembl ID		ENSG00000034713	ENSG00000188554
Uniprot IDs		P60520	A0A024R1V3 B7Z5R6 Q14596
PDB IDs		4CO7	1WJ6 2BKF 2CP8 2G4S 2L8J 2MGW 2MJ5 4OLE
Enriched GO Terms of Interacting Partners?
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