NONO and PLEKHF2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NONO	PLEKHF2
Description		non-POU domain containing octamer binding	pleckstrin homology and FYVE domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Membrane Nuclear Matrix Nuclear Speck Paraspeckles RNA Polymerase II Transcription Factor Complex	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Nucleic Acid Binding Chromatin Binding RNA Binding Protein Binding Identical Protein Binding E-box Binding	Protein Binding Phosphatidylinositol Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Activation Of Innate Immune Response DNA Repair DNA Recombination Regulation Of Transcription, DNA-templated MRNA Processing Circadian Rhythm RNA Splicing Regulation Of Circadian Rhythm Innate Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway	Protein Transport
Pathways
Drugs
Diseases
GWAS			Radiation response ( 20923822)
Interacting Genes		42 interacting genes: APBB1 AR BHLHE41 C11orf68 CA2 DDX6 DELEC1 ERG ESR1 EWSR1 FXR2 H3-4 IL7R IRAK3 LMO4 MAD1L1 MYC MYCN NUPR1 ORC5 OTUD5 PIN1 PLEKHF2 POLR2A PPP1CA PPP1CB PPP1CC PRKAA2 PRPF40A PSPC1 PTBP1 SFPQ SMARCB1 SMARCC1 SMARCD1 SPI1 SYNPO TCERG1 UBE2D1 UBE2I WBP4 ZNRD1	71 interacting genes: ACY3 AIDA AIMP2 APP APPL1 ARL14EP BEND7 BLOC1S6 BSCL2 CAVIN2 CCDC172 CCDC85B CEP44 CGGBP1 CHIC2 DPPA4 DRAP1 DTX2 DUT ESRP1 FBXO28 FHL3 FOXA1 FRMD8 GFER GLUL GNMT GPBP1 GPBP1L1 HEY1 HSPB7 L3MBTL3 LDOC1 MAX MBIP MEAF6 NKG7 NONO NPM2 PDP1 PEX2 PRDM14 PRKAR1A PRPSAP1 RAB39A RABAC1 RADX RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SEPTIN2 SEPTIN5 SEPTIN6 SETBP1 SFN SPEF1 TBX3 TCN2 TNFAIP8 TRAF6 TRAPPC3 TSC22D3 TXNL4B UBE2Z USF1 ZNF250 ZNF263 ZNF398
Entrez ID		4841	79666
HPRD ID		02098	15147
Ensembl ID		ENSG00000147140	ENSG00000175895
Uniprot IDs		A0A0S2Z4Z9 Q15233	Q9H8W4
PDB IDs		3SDE 5IFM
Enriched GO Terms of Interacting Partners?
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