MEOX2 and EFEMP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MEOX2	EFEMP2
Description		mesenchyme homeobox 2	EGF containing fibulin extracellular matrix protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm Nuclear Speck	Extracellular Region Basement Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding
	Biological Process	Angiogenesis Somite Specification Multicellular Organism Development Skeletal Muscle Tissue Development Blood Circulation Positive Regulation Of Transcription By RNA Polymerase II Roof Of Mouth Development Limb Development Somite Development Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis	Elastic Fiber Assembly
Pathways			Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs
Diseases			Cutis laxa, including: Autosomal dominant cutis laxa (ADCL); Autosomal recessive cutis laxa I (ARCL1); Autosomal recessive cutis laxa II (ARCL2); X-linked recessive cutis laxa (XRCL); Wrinkly skin syndrome
GWAS		Adolescent idiopathic scoliosis ( 31417091) Blood trace element (Zn levels) ( 23720494) Heel bone mineral density ( 30598549 28869591) Kidney function decline traits ( 25493955) Resting-state electroencephalogram vigilance ( 29703947) Total intracranial volume ( 31530798)	Acne (severe) ( 24927181) Birth weight ( 31043758)
Interacting Genes		244 interacting genes: - ACBD4 ACTN4 ADAMTS12 AGPAT1 AHCYL1 AHSA2P AMMECR1 ANP32B ARHGEF7 ARNT2 ATG5 ATXN1L AXIN1 BANP BCL2L15 BTK C1orf109 CARD9 CASP14 CCDC103 CCNC CDH9 CEP57L1 CHIC2 CHRD CHRNG CIAPIN1 CIB3 CNTNAP2 COG7 CPNE6 CPSF4 CRCT1 CSDC2 CSF2 CTNNBL1 CXXC1 DGCR6 DGCR8 DOCK8 DYNLL2 EDF1 EFEMP1 EFEMP2 EFNA3 EIF1AD EIF5A EMD EPM2AIP1 ESR2 ESRRG FAM126A FAM13C FAM3A FAM74A4 FANCC FANCG FBF1 FBLN5 FGA FKBP6 FOXR1 FUCA2 FUT11 GABRB3 GAGE1 GINS3 GLO1 GMCL2 GMPR2 GNG11 GOLGA8DP GOLGA8EP GOLGA8F GPATCH2L GPSM3 HAT1 HDHD2 HEXIM2 HGF HLA-A HNRNPD HP1BP3 HSPA2 HTR1E IGF2BP3 IGFN1 IL1A INPP1 IP6K2 ITM2A KAT5 KDM8 KIZ KLC4 KLHL38 KRT80 KRT86 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KTN1 LAMTOR5 LCE1B LCE2A LCE4A LSM2 MAGED1 MAPKBP1 MCM7 MDFI METTL17 MKRN3 MLF1 MLLT6 MMP3 MOBP MORN3 MRFAP1L1 MSI2 MT-CO1 MT-ND1 MT1DP MTMR10 MVP MYBPC1 NAA10 NALCN NCALD NCK2 NLGN3 NTF3 OIT3 OSGIN1 P4HA3 PACSIN2 PAGE2 PAK1IP1 PARVG PAX1 PAX3 PCDH9 PCSK5 PGBD1 PIN1 PKIG POM121C PRKAB2 PRKN PRPF31 PRR19 PSMB10 PSMC1 PSMD14 PTGER3 PWWP3A RARB RBM10 RBM5 RCHY1 RECK RHOJ RMND5A RND2 RNF40 RNF6 RPL15 RUNX1T1 SAMM50 SCNM1 SEC63 SELENOP SET SHFL SIRPB1 SLC48A1 SMAD3 SMARCE1 SPATA1 SPP1 SPRY1 SPRY2 SSX3 STK16 STX11 STX16 STXBP1 SYT17 TBCEL TBL2 TBX6 TCEA2 TCL6 TCTEX1D1 TDO2 TGFB1 TICAM2 TMEM100 TP53BP1 TRAF6 TRIM41 TRIM42 TTC25 TTC39B TTC9C TULP2 TXLNA UBE3A UBL4A UBL4B UNC45A UPP2 USE1 VDR VEZF1 VIP WFDC9 XRCC2 ZBED4 ZCWPW1 ZMAT2 ZNF124 ZNF329 ZNF404 ZNF417 ZNF483 ZNF564 ZNF572 ZNF587 ZNF688 ZNF695	52 interacting genes: AMMECR1 APEX2 AQP1 ATN1 ATXN1 ATXN7 BAG6 C5orf24 CACNA1A CATSPER1 CCDC33 CCND3 CCNK COL8A1 CREB5 DGCR6 FAM107A FAM124B FAM74A4 GFI1B GLRX3 HDAC4 HHEX HOXA1 IL16 LCE2D LCE3C LINGO1 MEOX2 NEDD4L NOS3 NUFIP2 PIDD1 PLSCR1 PLSCR4 PRPF31 PTGER3 RBPMS RERE RHOXF2 RHPN1 RIBC2 SGTA SGTB STK16 TCAF1 TP53 UBQLN1 UBQLN4 ZNF263 ZNF426 ZNF638
Entrez ID		4223	30008
HPRD ID		02760	05221
Ensembl ID		ENSG00000106511	ENSG00000172638
Uniprot IDs		P50222	A0A024R5G1 O95967 Q9H3D5
PDB IDs			2KL7
Enriched GO Terms of Interacting Partners?
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